Differential Requirements of NS4A for Internal NS3 Cleavage and Polyprotein Processing of Hepatitis C Virus (Q27481014)

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Yi-Ming Wang

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Tzu-Min Hung

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Shin C Chang

The hepatitis C virus and immune evasion: non-structural 3/4A transgenic mice are resistant to lethal tumour necrosis factor mediated liver disease

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publication date

August 2007

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7999-8008

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cites work

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Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease

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Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions

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Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites

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Kinetic and structural analyses of hepatitis C virus polyprotein processing

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An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A

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Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

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A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

20 March 2017

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The N-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A

20 March 2017

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Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells

20 March 2017

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Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation

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Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

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Cell transformation induced by hepatitis C virus NS3 serine protease

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Internal cleavage of hepatitis C virus NS3 protein is dependent on the activity of NS34A protease

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Internal processing of hepatitis C virus NS3 protein

29 September 2017

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2 June 2018

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2 June 2018

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A short form of the tick-borne encephalitis virus NS3 protein

2 June 2018

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Hepatitis C virus genotypes and the development of hepatocellular carcinoma

2 June 2018

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Hepatitis C virus NS4A inhibits cap-dependent and the viral IRES-mediated translation through interacting with eukaryotic elongation factor 1A.

27 November 2018

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Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

27 November 2018

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Hepatitis C virus (HCV) genotypes in Spanish patients with HCV infection: relationship between HCV genotype 1b, cirrhosis and hepatocellular carcinoma

27 November 2018

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A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease

27 November 2018

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The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor

27 November 2018

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[Hepatocyte transformation and tumor development induced by hepatitis C virus NS3 N-terminal protein]

27 November 2018

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