Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression (Q27477482)

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scientific article (publication date: September 2006)

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English	Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression	scientific article (publication date: September 2006)

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instance of

scholarly article

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title

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression (English)

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main subject

virology

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Hepatitis C virus

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based on heuristic

inferred from title

hepatitis C

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based on heuristic

inferred from title

author

John Hiscott

series ordinal

5

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Rongtuan Lin

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4

object named as

Rongtuan Lin

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author name string

Pasi Kaukinen

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1

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Maarit Sillanpää

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2

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Sergei Kotenko

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3

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Krister Melén

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6

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Ilkka Julkunen

series ordinal

7

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publication date

1 September 2006

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published in

Virology Journal

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volume

3

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issue

1

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page(s)

66

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cites work

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Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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21 March 2017

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21 March 2017

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon

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21 March 2017

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

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21 March 2017

The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis

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21 March 2017

Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

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21 March 2017

Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

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21 March 2017

Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines

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21 March 2017

Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription

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21 March 2017

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

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21 March 2017

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

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21 March 2017

Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets

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21 March 2017

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

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21 March 2017

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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21 March 2017

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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21 March 2017

VISA is an adapter protein required for virus-triggered IFN-beta signaling

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21 March 2017

Triggering the interferon antiviral response through an IKK-related pathway

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PubMed Central

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21 March 2017

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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PubMed Central

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21 March 2017

Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease

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PubMed Central

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21 March 2017

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

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PubMed Central

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21 March 2017

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

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PubMed Central

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7 April 2017

Evasion of intracellular host defence by hepatitis C virus

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PubMed Central

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7 April 2017

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

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PubMed Central

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7 April 2017

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

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PubMed Central

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7 April 2017

An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A

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PubMed Central

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7 April 2017

Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines

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PubMed Central

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29 September 2017

Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression.

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PubMed Central

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29 September 2017

Antiviral innate immunity pathways.

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PubMed Central

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29 September 2017

TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells.

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PubMed Central

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29 September 2017

Hepatitis C virus NS2 protein is phosphorylated by the protein kinase CK2 and targeted for degradation to the proteasome

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

Hepatitis C virus NS2 protein inhibits gene expression from different cellular and viral promoters in hepatic and nonhepatic cell lines.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

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29 September 2017

The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein

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PubMed Central

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29 September 2017

Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs

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PubMed Central

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29 September 2017

Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7.

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PubMed Central

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29 September 2017

Characterization of cell lines allowing tightly regulated expression of hepatitis C virus core protein

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PubMed Central

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29 September 2017

Structural biology of hepatitis C virus

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PubMed Central

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27 November 2018

Membrane topology of the hepatitis C virus NS2 protein

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PubMed Central

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27 November 2018

Virus infection activates IL-1 beta and IL-18 production in human macrophages by a caspase-1-dependent pathway.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569370

retrieved

27 November 2018

Identifiers

DOI

10.1186/1743-422X-3-66

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Dimensions Publication ID

1031702285

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Fatcat ID

release_cgagvbecjfctvkenpil7lp5axe

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PMC publication ID

1569370

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PubMed publication ID

16945160

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