Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes (Q27324311)

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Alison E Mungenast

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Yuan-Ta Lin

0 references

Tak Ko

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Fatema Abdurrob

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Jinsoo Seo

Creative Commons Attribution 4.0 International

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language of work or name

English

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publication date

2016

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e0161969

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start time

13 September 2016

1 reference

April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5021368/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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28 September 2017

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28 September 2017

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28 September 2017

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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A three-dimensional human neural cell culture model of Alzheimer's disease

28 September 2017

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2 June 2018

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Modeling familial Alzheimer's disease with induced pluripotent stem cells

2 June 2018

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Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories

2 June 2018

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2 June 2018

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2 June 2018

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The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

2 June 2018

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A phase 3 trial of semagacestat for treatment of Alzheimer's disease

2 June 2018

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Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

21 January 2018

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Lessons from a failed γ-secretase Alzheimer trial

21 January 2018

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Modeling human disease with pluripotent stem cells: from genome association to function.

21 January 2018

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Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0161969

Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

21 January 2018

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EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs

21 January 2018

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Next-generation regenerative medicine: organogenesis from stem cells in 3D culture

21 January 2018

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A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0161969

APP processing is regulated by cytoplasmic phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0161969

A new dynamic in vitro model for the multidimensional study of astrocyte-endothelial cell interactions at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0161969

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0161969

Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021368

Getting active: protein sorting in endocytic recycling

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27622770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27622770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0161969

1 reference

ADS bibcode

2016PLoSO..1161969R

0 references

1 reference

1 reference

PubMed publication ID

27622770

1 reference