Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival (Q27313215)

From Wikidata

Jump to navigation Jump to search

scientific article published on October 7, 2010

Language	Label	Description	Also known as
English	Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival	scientific article published on October 7, 2010

Statements

scholarly article

0 references

Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival (English)

0 references

Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival (English)

1 reference

10.1371/JOURNAL.PPAT.1001138

https://api.crossref.org/works/10.1371/JOURNAL.PPAT.1001138

3 August 2024

prion protein family

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

Calcineurin Inhibitors

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

author name string

Abhisek Mukherjee

1

0 references

Diego Morales-Scheihing

2

0 references

Dennisse Gonzalez-Romero

3

0 references

Kristi Green

4

0 references

Giulio Taglialatela

5

0 references

Claudio Soto

6

0 references

language of work or name

0 references

publication date

2010

0 references

7 October 2010

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

full work available at URL

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001138&type=printable

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20949081/?tool=EBI

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20949081/pdf/?tool=EBI

Portable Document Format

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

https://europepmc.org/articles/PMC2951383

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

https://europepmc.org/articles/PMC2951383?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20949081

3 August 2024

http://dx.plos.org/10.1371/journal.ppat.1001138

1 reference

10.1371/JOURNAL.PPAT.1001138

https://api.crossref.org/works/10.1371/JOURNAL.PPAT.1001138

3 August 2024

0 references

6

0 references

10

0 references

e1001138

0 references

copyright license

Creative Commons Attribution 4.0 International

7 October 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Evaluation of quinacrine treatment for prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

The allograft inflammatory factor-1 in Creutzfeldt-Jakob disease brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Prion diseases of humans and animals: their causes and molecular basis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

NeuN, a neuronal specific nuclear protein in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Prions: protein aggregation and infectious diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Degenerating synaptic boutons in prion disease: microglia activation without synaptic stripping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Recent advances in prion chemotherapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Cell-free propagation of prion strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

A systematic review of prion therapeutics in experimental models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

The role of the endoplasmic reticulum in the accumulation of beta-amyloid peptide in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Stressing out the ER: a role of the unfolded protein response in prion-related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Sourcing a chemical succession for cyclosporin from parasites and human pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

In vitro generation of infectious scrapie prions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Approaches to therapy of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Misfolded proteins, endoplasmic reticulum stress and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Prion diseases--close to effective therapy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Diagnosing prion diseases: needs, challenges and hopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Calcineurin: a central controller of signalling in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Calcineurin in memory and bidirectional plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Calcineurin regulation of neuronal plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Tacrolimus: a further update of its use in the management of organ transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Atypical inflammation in the central nervous system in prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Rapamycin in transplantation: a review of the evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Use of thapsigargin to study Ca2+ homeostasis in cardiac cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Amphotericin B delays both scrapie agent replication and PrP-res accumulation early in infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Experimental scrapie in the mouse: a review of an important model disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Transport of prion protein across the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Calcineurin in human brain and its relation to extrapyramidal system. Immunohistochemical study on postmortem human brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Chemoprophylaxis of scrapie in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Early behavioural changes in scrapie-affected mice and the influence of dapsone

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Vacuolation in murine prion disease: an informative artifact.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Results of quinacrine administration to patients with Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

MS-8209, an amphotericin B analogue, delays the appearance of spongiosis, astrogliosis and PrPres accumulation in the brain of scrapie-infected hamsters

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Less protease-resistant PrP in a patient with sporadic CJD treated with intraventricular pentosan polysulphate

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Continuous intraventricular infusion of pentosan polysulfate: clinical trial against prion diseases

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Failure to ameliorate Creutzfeldt-Jakob disease with amphotericin B therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949081

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraventricular pentosan polysulphate in human prion diseases: an observational study in the UK

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949081

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluoro-Jade: novel fluorochromes for detecting toxicant-induced neuronal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949081

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1001138

0 references

PMC publication ID

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27313215&oldid=2219449321"