Computer-assisted structure verification and elucidation tools in NMR-based structure elucidation (Q27156499)

Chemical Similarity Searching

Web of Science

1 reference

https://opencitations.net/index/coci/api/v1/citations/10.1021/CI9800211

Logic for structure determination

12 September 2021

1 reference

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0040-4020(01)80878-4

“Connectivist” approach to organic structure determination Lsd-program assisted Nmr analysis of the insect antifeedant Azadirachtin

10 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0040-4020(01)89576-4

Known and novel terpenes from Buddleja globosa displaying selective antifungal activity against dermatophytes

10 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

New Semi-empirical Approach for the Calculation of13C Chemical-Shift Tensors

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Towards the automatic analysis of 1H NMR spectra: Part 4--additional requirements of flow-NMR.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Structure Elucidator: a versatile expert system for molecular structure elucidation from 1D and 2D NMR data and molecular fragments

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Computer-aided spectral assignment in nuclear magnetic resonance spectroscopy

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Fast determination of 13C NMR chemical shifts using artificial neural networks

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Cryptospirolepine, a Unique Spiro-nonacyclic Alkaloid Isolated from Cryptolepis sanguinolenta

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Elucidation of the structure of quindolinone, a minor alkaloid ofcryptolepis sanguinolenta: Submilligram1H-13c and1H-15N heteronuclear shift correlation experiments using micro inverse-detection

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Identification of Two Chromenes fromCalea serrataby Semiautomatic Structure Elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Elucidation by progressive intersection of ordered substructures from carbon-13 nuclear magnetic resonance

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Limonoid derivatives from Astrotrichilia voamatata

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

The isolation and structure determination of cryptomisrine, a novel indolo[3,2-b]quinoline dimeric alkaloid fromcryptolepis sanguinolenta

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Applications of artificial intelligence for chemical inference. I. Number of possible organic compounds. Acyclic structures containing carbon, hydrogen, oxygen, and nitrogen

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

CSEARCH: a computer program for identification of organic compounds and fully automated assignment of carbon-13 nuclear magnetic resonance spectra

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Tricyclic sesquiterpenes from rudbeckia laciniata in honour of professor G. H. Neil Towers 75th birthday

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Two new indoloquinoline alkaloids fromcryptolepis sanguinolenta: Cryptosanguinolentine and cryptotackieine

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

New cembranes from Cleome spinosa

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Neural network studies. 4. Introduction to associative neural networks.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Long-Range 1H–15N Heteronuclear Shift Correlation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Computer-aided determination of relative stereochemistry and 3D models of complex organic molecules from 2D NMR spectra

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

A Mathematical Theory of Communication

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Automated structure verification based on 1H NMR prediction.

10 July 2022

2 references

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

10 July 2022

https://opencitations.net/index/coci/api/v1/citations/10.1002/MRC.1781

Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine CyanobacteriumPhormidiumsp.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Isolation and elucidation of the structure of homocryptolepinone

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Novel methods of automated structure elucidation based on 13C NMR spectroscopy.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Mathematical synthesis and analysis of molecular structures

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Structure generation by reduction: a new strategy for computer-assisted structure elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Long-range (1)H-(15)N heteronuclear shift correlation at natural abundance

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Principles of the Generation of Constitutional and Configurational Isomers

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

An expert system for automated structure elucidation utilizing 1H-1H, 13C-1H and 15N-1H 2D NMR correlations.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Apramides A-G, novel lipopeptides from the marine cyanobacterium Lyngbya majuscula

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

2J,(3)J-HMBC: A new long-range heteronuclear shift correlation technique capable of differentiating (2)J(CH) from (3)J(CH) correlations to protonated carbons

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Structure-based predictions of 1H NMR chemical shifts using feed-forward neural networks.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Automatic generation of 3D-atomic coordinates for organic molecules

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

The impact of available experimental data on the prediction of 1H NMR chemical shifts by neural networks

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

HMBC-RELAY: a combined technique for the differentiation of simultaneously detected 2J(C,H) and (n)J(C,H) connectivities

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Computer-assisted constitutional assignment of large molecules: COCON analysis of ascomycin

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Identification of degradants of a complex alkaloid using NMR cryoprobe technology and ACD/structure elucidator

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

NMR studies of structure and function of biological macromolecules (Nobel lecture)

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Tasiamide, a cytotoxic peptide from the marine cyanobacterium Symploca sp

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Using neural networks for (13)c NMR chemical shift prediction-comparison with traditional methods

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Applying the constraint satisfaction problem paradigm to structure generation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

New cytotoxic indolic metabolites from a marine Streptomyces

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Automated structure elucidation of organic molecules from (13)c NMR spectra using genetic algorithms and neural networks.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Stochastic Generator of Chemical Structure. 2. Using Simulated Annealing To Search the Space of Constitutional Isomers

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Two‐dimensional spectroscopy. Application to nuclear magnetic resonance

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Are deterministic expert systems for computer-assisted structure elucidation obsolete?

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

The structure of Palau'amide, a potent cytotoxin from a species of the marine cyanobacterium Lyngbya

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Genius: a genetic algorithm for automated structure elucidation from 13C NMR spectra

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Isolation and structure elucidation of deformylflustrabromine from the North Sea bryozoan Flustra foliacea

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Chemistry of sponges. 19. Novel bioactive metabolites from Hamigera tarangaensis

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Dendral and meta-dendral — the myth and the reality

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Norditerpenoid alkaloids from Aconitella hohenackeri

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Assemble 2.0: a structure generator

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

HOSE — a novel substructure code

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Isolation of four new cyclic depsipeptides, antanapeptins A-D, and dolastatin 16 from a Madagascan collection of Lyngbya majuscula

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Isolation of homodolastatin 16, a new cyclic depsipeptide from a Kenyan collection of Lyngbya majuscula

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Application of the computer program GENOA and two-dimensional NMR spectroscopy to structure elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Oxepinamides A-C and fumiquinazolines H--I: bioactive metabolites from a marine isolate of a fungus of the genus Acremonium

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

MOLGEN+, a generator of connectivity isomers and stereoisomers for molecular structure elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the volsurf approach

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Ingenamine G and cyclostellettamines G-I, K, and L from the new Brazilian species of marine sponge Pachychalina sp.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Automated structure elucidation - the benefits of a symbiotic relationship between the spectroscopist and the expert system

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Coproverdine, a novel, cytotoxic marine alkaloid from a new zealand ascidian.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Expectation ranges of 13C NMR chemical shifts

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Bioactive natural products from a sclerotium-colonizing isolate of Humicola fuscoatra

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Comprehensive parameter set for the prediction of the 13C-NMR chemical shifts of sp3-hybridized carbon atoms in organic compounds

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Towards the automatic analysis of NMR spectra: part 6. Confirmation of chemical structure employing both 1H and 13C NMR spectra

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Improved Sensitivity in Gradient-Based 1D and 2D Multiplicity-Edited HSQC Experiments

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Case, a computer model of the structure elucidation process

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

15N NMR Spectroscopy in Structural Analysis

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Prediction of 1H NMR Chemical Shifts Using Neural Networks

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Computer-assisted structure elucidation of natural products with limited 2D NMR data: application of the StrucEluc system

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

HOUDINI: A New Approach to Computer-Based Structure Generation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Validation of Structural Proposals by Substructure Analysis and13C NMR Chemical Shift Prediction

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Quindolinocryptotackieine: the elucidation of a novel indoloquinoline alkaloid structure through the use of computer-assisted structure elucidation and 2D NMR

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Clerodane diterpenoids and an ursane triterpenoid from Salvia haenkei. Computer-assisted structural elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

On the use of neural network ensembles in QSAR and QSPR.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Computer-Based Structure Determination: Then and Now

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Stenocarpine, a diterpenoid alkaloid from Aconitella stenocarpa

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Isomer generators in structure elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Fully Automated Structure ElucidationA Spectroscopist's Dream Comes True†

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Detection of connectivity between equivalent carbons in aC2 molecule using isotopomeric asymmetry: Identification of hopeaphenol inCarex pumila

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Applications of a HOUDINI-Based Structure Elucidation System

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

SENECA: A Platform-Independent, Distributed, and Parallel System for Computer-Assisted Structure Elucidation in Organic Chemistry

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

The Assignment of Absolute Configuration by NMR

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Malevamide D: isolation and structure determination of an isodolastatin H analogue from the marine cyanobacterium Symploca hydnoides

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Application of a new expert system for the structure elucidation of natural products from their 1D and 2D NMR data

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Comparison of Automatic Three-Dimensional Model Builders Using 639 X-ray Structures

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Optimization by Simulated Annealing

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Structure elucidation from 2D NMR spectra using the StrucEluc expert system: detection and removal of contradictions in the data

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Application of the Maximal Common Substructure Algorithm to Automatic Interpretation of 13C-NMR Spectra

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

New antifeedant bromopyrrole alkaloid from the Caribbean sponge Stylissa caribica

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Durhamycin A, a potent inhibitor of HIV Tat transactivation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Applications of artificial intelligence for chemical inference. 37. GENOA: a computer program for structure elucidation utilizing overlapping and alternative substructures

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

The CSEARCH-NMR data base approach to solve frequent questions concerning substituent effects on 13C NMR chemical shifts

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Computer-assisted structural elucidation. Alkaloids with a novel diaza-adamantane skeleton from the seeds of Acosmium panamense (Fabaceae)

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Sesquiterpene metabolites of the antarctic gorgonian Dasystenella acanthina

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

New minor taxane derivatives from the needles of Taxus canadensis

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Fuzzy structure generation: a new efficient tool for Computer-Aided Structure Elucidation (CASE).

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Delevoyin C, a tetranortriterpenoid from Entandrophragma delevoyi.

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Gradient selection in inverse heteronuclear correlation spectroscopy

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

1H-NMR and 13C-NMR Assignments of Cryptolepine, A 3:4-Benz-delta-carboline Derivative Isolated from Cryptolepis sanguinolenta

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Maximum common subgraph isomorphism algorithms for the matching of chemical structures

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Evolutionary-Algorithm-Based Strategy for Computer-Assisted Structure Elucidation

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

LUCY—A Program for Structure Elucidation from NMR Correlation Experiments

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003

Recent developments in automated structure elucidation of natural products

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1016/J.PNMRS.2007.04.003