TLRs and interferons: a central paradigm in autoimmunity (Q27023982)

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

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Type I IFN protects against murine lupus

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C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

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Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms

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Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

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Pharmacogenomics and translational simulations to bridge indications for an anti-interferon-α receptor antibody

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PubMed publication ID

24246388

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