S-adenosylmethionine (SAMe) therapy in liver disease: a review of current evidence and clinical utility (Q26829356)

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3 February 2020

title

S-adenosylmethionine (SAMe) therapy in liver disease: a review of current evidence and clinical utility (English)

2 references

PubMed

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3 February 2020

1 reference

1 reference

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3 February 2020

Christopher P Day

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3 February 2020

language of work or name

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30 May 2012

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3 February 2020

published in

Journal of Hepatology

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PubMed

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3 February 2020

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3 February 2020

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3 February 2020

page(s)

1097-1109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22659519%20AND%20SRC:MED&resulttype=core&format=json

Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial

3 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Reversal of intrahepatic cholestasis of pregnancy in women after high dose S-adenosyl-L-methionine administration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Specific loss of the high-molecular-weight form of S-adenosyl-L-methionine synthetase in human liver cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Apoptosis and necrosis in the liver: a tale of two deaths?

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Role of S-adenosyl-L-methionine in liver health and injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low-density lipoprotein assembly in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Nitric oxide inactivates rat hepatic methionine adenosyltransferase In vivo by S-nitrosylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

The role of S-adenosylmethionine in preventing oxaliplatin-induced liver toxicity: a retrospective analysis in metastatic colorectal cancer patients treated with bevacizumab plus oxaliplatin-based regimen

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Pathogenesis of methionine-induced toxicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Methionine adenosyltransferase: structure and function

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine versus ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy: preliminary results of a controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Parenchymal extinction: coagulation and hepatic fibrogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

ESPEN Guidelines on Enteral Nutrition: Liver disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Association of nonalcoholic fatty liver disease with insulin resistance.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Consensus nomenclature for the mammalian methionine adenosyltransferase genes and gene products

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice☆

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

1 reference

7 January 2021

Effect of S-adenosyl-L-methionine and dilinoleoylphosphatidylcholine on liver lipid composition and ethanol hepatotoxicity in isolated perfused rat liver.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Effect of S-adenosylmethionine versus tauroursodeoxycholic acid on bile acid-induced apoptosis and cytolysis in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

A randomised controlled trial of ursodeoxycholic acid and S-adenosyl-l-methionine in the treatment of gestational cholestasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

AGA technical review on nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Cellular and molecular mechanisms of liver injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-Adenosyl Methionine Improves Early Viral Responses and Interferon-Stimulated Gene Induction in Hepatitis C Nonresponders

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Alcoholic liver disease: pathogenesis and new therapeutic targets

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Oxidative stress and the pathogenesis of cholestasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Genetics of alcoholic and nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Identification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Phospholipid methylation: a biochemical signal modulating lymphocyte mitogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

The X protein of hepatitis B virus inhibits apoptosis in hepatoma cells through enhancing the methionine adenosyltransferase 2A gene expression and reducing S-adenosylmethionine production

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Interaction of liver methionine adenosyltransferase with hydroxyl radical

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-Adenosylmethionine: a control switch that regulates liver function.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Abnormal hepatic methionine and glutathione metabolism in patients with alcoholic hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

A randomised placebo-controlled trial of ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Role of apoptosis in alcoholic liver injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Phospholipid Methylation and Biological Signal Transmission

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

How big a problem is non-alcoholic fatty liver disease?

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Is liver fibrosis reversible?

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Effects of prolonged ethanol feeding on methionine metabolism in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

STUDIES IN METHIONINE AND SULFUR METABOLISM. I. THE FATE OF INTRAVENOUSLY ADMINISTERED METHIONINE, IN NORMAL INDIVIDUALS AND IN PATIENTS WITH LIVER DAMAGE.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

The Role of Acetaldehyde in Mediating the Deleterious Effect of Ethanol on Pyridoxal 5′-Phosphate Metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Intrahepatic cholestasis of pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

The role of S-adenosyl methionine in preventing FOLFOX-induced liver toxicity: a retrospective analysis in patients affected by resected colorectal cancer treated with adjuvant FOLFOX regimen

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

Vitamin-dependent methionine metabolism and alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.04.041

7 January 2021

S-adenosyl-L-methionine for alcoholic liver diseases

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1002/14651858.CD002235.PUB2

Identifiers

DOI

10.1016/J.JHEP.2012.04.041

2 references

Consolidated OpenCitations Corpus – April 2017

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3 February 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

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