Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics (Q26782928)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26468188%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics (English)

1 reference

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27 February 2020

0 references

1 reference

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27 February 2020

Ream Al-Hasani

1 reference

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27 February 2020

Tuan Trang

1 reference

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27 February 2020

Daniela Salvemini

series ordinal

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27 February 2020

Michael W Salter

series ordinal

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27 February 2020

Howard Gutstein

series ordinal

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27 February 2020

language of work or name

English

0 references

publication date

1 October 2015

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27 February 2020

published in

Journal of Neuroscience

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27 February 2020

volume

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27 February 2020

issue

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27 February 2020

page(s)

13879-13888

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Cell signaling by receptor tyrosine kinases

27 February 2020

cites work

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Microglia disrupt mesolimbic reward circuitry in chronic pain.

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain.

28 September 2017

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P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation

28 September 2017

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Neuropathic pain: quality-of-life impact, costs and cost effectiveness of therapy

28 September 2017

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28 September 2017

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Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain.

28 September 2017

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Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)

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Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trial

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Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain

28 September 2017

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Ventral tegmental area neurons in learned appetitive behavior and positive reinforcement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Nucleoside transporters: from scavengers to novel therapeutic targets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Abuse of prescription drugs and the risk of addiction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment

28 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

28 September 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Role of the immune system in chronic pain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

State-dependent opioid control of pain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Glia: a novel drug discovery target for clinical pain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Neuropathological imaging: in vivo detection of glial activation as a measure of disease and adaptive change in the brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

A3 adenosine receptor as a target for cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Spinal cord neuroplasticity following repeated opioid exposure and its relation to pathological pain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Glial activation: a driving force for pathological pain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

GABA(A) receptors in the ventral tegmental area control bidirectional reward signalling between dopaminergic and non-dopaminergic neural motivational systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Adenosine A3 receptors: novel ligands and paradoxical effects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

28 September 2017

Adenosine transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Opiate reward: sites and substrates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Mechanisms of opioid actions on neurons of the locus coeruleus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurones

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Targeting microglial purinergic signaling to improve morphine analgesia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Opiate state controls bi-directional reward signaling via GABAA receptors in the ventral tegmental area

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Presynaptic inhibition of GABA(B)-mediated synaptic potentials in the ventral tegmental area during morphine withdrawal

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

A Range of Research-Based Pharmacotherapies for Addiction

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Activation of mu opioid receptors inhibits microglial cell chemotaxis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

A common mechanism mediates long-term changes in synaptic transmission after chronic cocaine and morphine

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Cyclic adenosine monophosphate antagonism of morphine analgesia.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Autoradiographic localization of mu, delta and kappa opioid receptor binding sites in rat and guinea pig spinal cord

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Effects of (-)-N6-(R-phenylisopropyl)-adenosine (PIA) and caffeine on nociception and morphine-induced analgesia, tolerance and dependence in mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Distinct distribution of opioid receptor types in rat lumbar spinal cord

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Stereospecificity in some central and circulatory effects of phenylisopropyl-adenosine (PIA)

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Microglial activation involved in morphine tolerance is not mediated by toll-like receptor 4.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

A novel role of minocycline: attenuating morphine antinociceptive tolerance by inhibition of p38 MAPK in the activated spinal microglia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Brain regional Fos expression elicited by the activation of mu- but not delta-opioid receptors of the ventral tegmental area: evidence for an implication of the ventral thalamus in opiate reward

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Plasticity of reward neurocircuitry and the 'dark side' of drug addiction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Intrathecal morphine reduces allodynia after peripheral nerve injury in rats via activation of a spinal A1 adenosine receptor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Increased nociceptive response in mice lacking the adenosine A1 receptor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Intrathecal but not intravenous opioids release adenosine from the spinal cord

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Suppression of the morphine-induced rewarding effect in the rat with neuropathic pain: implication of the reduction in mu-opioid receptor functions in the ventral tegmental area

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Motivational state determines the functional role of the mesolimbic dopamine system in the mediation of opiate reward processes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

The mu-opioid receptor (MOR1) is mainly restricted to neurons that do not contain GABA or glycine in the superficial dorsal horn of the rat spinal cord

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604226

Antinociceptive effects in mice after intrathecal injection of 5′-N-ethylcarboxamide adenosine

28 November 2018

1 reference

12 December 2020

Effects of some adenosine analogs on morphine-induced analgesia and tolerance

1 reference

12 December 2020

Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice

1 reference

12 December 2020

Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine

1 reference

12 December 2020

Influence of adenosine analogs on morphine tolerance and dependence in mice

1 reference

12 December 2020

Regulation and function of adenosine deaminase in mice

1 reference

12 December 2020

Chronic pain in Australia: a prevalence study

1 reference

12 December 2020

Increased probability of GABA release during withdrawal from morphine

1 reference

12 December 2020

Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat

1 reference

12 December 2020

Effects of cyclic 3',5'-adenosine monophosphate on morphine tolerance and physical dependence

1 reference

12 December 2020

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat

1 reference

12 December 2020

Morphine releases endogenous adenosine from the spinal cord in vivo

1 reference

12 December 2020

10.1523/JNEUROSCI.2711-15.2015

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yub7bp2e7jhwfmdt246dfkjwey

30 July 2022

release_yub7bp2e7jhwfmdt246dfkjwey

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yub7bp2e7jhwfmdt246dfkjwey

30 July 2022

OpenCitations bibliographic resource ID

2666355

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://api.fatcat.wiki/v0/release/yub7bp2e7jhwfmdt246dfkjwey

30 July 2022

https://api.fatcat.wiki/v0/release/yub7bp2e7jhwfmdt246dfkjwey

PubMed publication ID

1 reference

30 July 2022