A Review of Animal Models of Intervertebral Disc Degeneration: Pathophysiology, Regeneration, and Translation to the Clinic (Q26744550)

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14 March 2020

review article

4 references

24 June 2020

30 September 2020

3 December 2020

A Review of Animal Models of Intervertebral Disc Degeneration: Pathophysiology, Regeneration, and Translation to the Clinic (English)

1 reference

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degenerative disc disease

14 March 2020

main subject

8 references

13 March 2019

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22 June 2019

19 September 2019

6 October 2019

11 October 2019

24 June 2020

30 September 2020

biomedical investigative technique

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human musculoskeletal system

19 September 2019

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6 October 2019

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11 October 2019

1 reference

translational medical research

1 reference

30 September 2020

1 reference

3 December 2020

1 reference

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14 March 2020

1 reference

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14 March 2020

1 reference

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14 March 2020

1 reference

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14 March 2020

Peter Ghosh

1 reference

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14 March 2020

language of work or name

English

0 references

publication date

22 May 2016

10 references

13 March 2019

20 June 2019

22 June 2019

19 September 2019

6 October 2019

11 October 2019

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14 March 2020

24 June 2020

30 September 2020

3 December 2020

BioMed Research International

11 references

13 March 2019

20 June 2019

22 June 2019

19 September 2019

6 October 2019

11 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27314030%20AND%20SRC:MED&resulttype=core&format=json

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24 June 2020

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2016

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14 March 2020

page(s)

5952165

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Creative Commons Attribution 4.0 International

14 March 2020

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13 March 2019

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22 June 2019

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6 October 2019

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24 June 2020

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on focus list of Wikimedia project

3 December 2020

copyrighted

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ScienceSource

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cites work

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Are animal models useful for studying human disc disorders/degeneration?

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Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration

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The dog as an animal model for intervertebral disc degeneration?

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CD44 expression in the developing and growing rat intervertebral disc.

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Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model

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Cervical interbody fusion is enhanced by allogeneic mesenchymal precursor cells in an ovine model.

21 January 2018

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Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc

21 January 2018

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Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat.

21 January 2018

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Magnetic resonance classification of lumbar intervertebral disc degeneration.

21 January 2018

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Evaluation of intervertebral disk degeneration in chondrodystrophic and nonchondrodystrophic dogs by use of Pfirrmann grading of images obtained with low-field magnetic resonance imaging

21 January 2018

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Effect of chondroitinase ABC on matrix metalloproteinases and inflammatory mediators produced by intervertebral disc of rabbit in vitro

21 January 2018

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Reconstitution of degenerated ovine lumbar discs by STRO-3-positive allogeneic mesenchymal precursor cells combined with pentosan polysulfate.

21 January 2018

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Degenerative changes of porcine intervertebral disc induced by vertebral endplate injuries.

21 January 2018

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Lateral surgical approach to lumbar intervertebral discs in an ovine model.

21 January 2018

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Fresh frozen intervertebral disc allografting in a bipedal animal model

21 January 2018

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Puncture of a lumbar intervertebral disc induces changes in spontaneous pain behavior: an experimental study in rats

21 January 2018

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Premature Vertebral Endplate Ossification and Mild Disc Degeneration in Mice After Inactivation of One Allele Belonging to the Col2a1 Gene for Type II Collagen

21 January 2018

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Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model.

21 January 2018

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28 November 2018

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Experimental Cervical Spondylosis in the Mouse

28 November 2018

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Intervertebral disc mechanics are restored following cyclic loading and unloaded recovery

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Pathogenesis of sciatic pain: role of herniated nucleus pulposus and deformation of spinal nerve root and dorsal root ganglion

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Low back pain in relation to lumbar disc degeneration

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ENZYME DISSOLUTION OF THE NUCLEUS PULPOSUS IN HUMANS

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Regeneration of intervertebral discs in a rat disc degeneration model by implanted adipose-tissue-derived stromal cells

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Bipedal rats and mice; laboratory animals for orthopaedic research

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A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model

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The sand rat model for disc degeneration: radiologic characterization of age-related changes: cross-sectional and prospective analyses

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Progressive degeneration of articular cartilage and intervertebral discs. An experimental study in transgenic mice bearing a type IX collagen mutation

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Comparison of animals used in disc research to human lumbar disc geometry

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The origin and fate of herniated lumbar intervertebral disc tissue

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Are sheep spines a valid biomechanical model for human spines?

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Histologic and morphometric observations on vertebral bone of aging sand rats

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Spontaneous disc degeneration in the baboon model: magnetic resonance imaging and histopathologic correlation

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Intervertebral disc degeneration adjacent to a lumbar fusion. An experimental rabbit model

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Anatomy of the sheep spine and its comparison to the human spine

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The dynamics of experimental posture. Experimental study of intervertebral disk herniation in bipedal animals

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Intervertebral-disc degeneration considered as a pressure atrophy

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Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs

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Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis

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12 December 2020

New In Vivo Animal Model to Create Intervertebral Disc Degeneration and to Investigate the Effects of Therapeutic Strategies to Stimulate Disc Regeneration

2 references

12 December 2020

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7 January 2021

inferred from DOI database lookup

Experimental intervertebral disc degeneration induced by chondroitinase ABC in the goat

1 reference

12 December 2020

A New Porcine In Vivo Animal Model of Disc Degeneration

1 reference

12 December 2020

Chymopapain, chemonucleolysis, and nucleus pulposus regeneration. A biochemical and biomechanical study

1 reference

12 December 2020

An in vivo model of degenerative disc disease

1 reference

12 December 2020

Mesenchymal progenitor cells combined with pentosan polysulfate mediating disc regeneration at the time of microdiscectomy: a preliminary study in an ovine model

1 reference

12 December 2020

Mechanical Destabilization Induced by Controlled Annular Incision of the Intervertebral Disc Dysregulates Metalloproteinase Expression and Induces Disc Degeneration

1 reference

12 December 2020

Treatment of lumbar intervertebral disc lesions by direct injection of chymopapain

1 reference

12 December 2020

The effect of cyclic compression on the mechanical properties of the inter-vertebral disc: an in vivo study in a rat tail model

1 reference

12 December 2020

Degeneration of the intervertebral disks and spondylosis in aging sand rats

1 reference

12 December 2020

Investigation of the laminate structure of lumbar disc anulus fibrosus

1 reference

12 December 2020

Intervertebral disc reconstitution after chemonucleolysis with chymopapain is dependent on dosage

1 reference

12 December 2020

Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison

1 reference

12 December 2020

Age-related changes in the beagle spine

1 reference

12 December 2020

Disc regeneration therapy using marrow mesenchymal cell transplantation: a report of two case studies

1 reference

12 December 2020

Changes in the nucleus pulposus of the intervertebral disc in bipedal mice. A light and electron microscopic study

1 reference

12 December 2020

Some experimental observations of the influence of a single lumbar floating fusion on the remaining lumbar spine

1 reference

12 December 2020

1 reference

12 December 2020

Intervertebral disc autografting in a bipedal animal model

1 reference

12 December 2020

Fibronectin and its fragments increase with degeneration in the human intervertebral disc

1 reference

12 December 2020

A comparison between bipedal and quadrupedal rats: do bipedal rats actually assume an upright posture?

1 reference

12 December 2020

Identifiers

DOI

10.1155/2016/5952165

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27314030%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27314030%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PubMed publication ID

27314030

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27314030%20AND%20SRC:MED&resulttype=core&format=json