Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1 (Q26269957)

19 October 2023

C Rosenmund

Rosenmund

1 reference

19 October 2023

J-S Rhee

J-S

Rhee

1 reference

19 October 2023

L Y Li

L Y

1 reference

19 October 2023

O-H Shin

series ordinal

author given names

O-H

author last names

Shin

1 reference

19 October 2023

J-C Rah

series ordinal

author given names

J-C

author last names

Rah

1 reference

19 October 2023

J Rizo

series ordinal

author given names

author last names

Rizo

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

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publication date

20 December 2005

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published in

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volume

102

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issue

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page(s)

18664-9

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cites work

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Synaptotagmin I functions as a calcium regulator of release probability

7 April 2017

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7 April 2017

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Definition of the readily releasable pool of vesicles at hippocampal synapses

7 April 2017

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C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I.

28 September 2017

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The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis.

28 September 2017

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The C2B domain of synaptotagmin is a Ca(2+)-sensing module essential for exocytosis

28 September 2017

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Interaction of the synprint site of N-type Ca2+ channels with the C2B domain of synaptotagmin I.

28 September 2017

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Synaptotagmins: C2-domain proteins that regulate membrane traffic

28 September 2017

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Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca(2+)-activated neurotransmitter release.

28 September 2017

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Synaptic transmission persists in synaptotagmin mutants of Drosophila

28 September 2017

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28 September 2017

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A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization

28 September 2017

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Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin

31 May 2018

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Ca2+ regulates the interaction between synaptotagmin and syntaxin 1.

31 May 2018

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Distinct Ca(2+)-dependent properties of the first and second C2-domains of synaptotagmin I.

21 January 2018

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Synaptotagmins I and IV promote transmitter release independently of Ca(2+) binding in the C(2)A domain

21 January 2018

1 reference

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The effects of temperature on vesicular supply and release in autaptic cultures of rat and mouse hippocampal neurons

21 January 2018

1 reference

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Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509153102

Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509153102

PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509153102

The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509153102

Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509153102

NMR measurement of the off rate from the first calcium-binding site of the synaptotagmin I C2A domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509153102

Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1

21 January 2018

1 reference

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An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system

28 November 2018

1 reference

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Localization of synaptotagmin-binding domains on syntaxin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1311909

Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1311909

Lipids of synaptic vesicles: relevance to the mechanism of membrane fusion

28 November 2018

1 reference

12 December 2020

Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C

1 reference

12 December 2020

Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I

1 reference

12 December 2020

Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes

1 reference

12 December 2020

Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells

1 reference

12 December 2020

Facile detection of protein-protein interactions by one-dimensional NMR spectroscopy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0509153102

1 reference

ADS bibcode

2005PNAS..10218664R

0 references

1 reference

1 reference

1 reference