Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal (Q24813445)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16106044%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal (English)

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5 January 2020

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5 January 2020

Jing Li

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5 January 2020

John J Correia

series ordinal

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5 January 2020

Lei Wang

series ordinal

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5 January 2020

John O Trent

series ordinal

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5 January 2020

language of work or name

English

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publication date

16 August 2005

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5 January 2020

published in

Nucleic Acids Research

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5 January 2020

volume

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5 January 2020

issue

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5 January 2020

page(s)

4649-4659

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Covalent ligation studies on the human telomere quadruplex

5 January 2020

cites work

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

7 April 2017

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Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems

7 April 2017

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Calculation of hydrodynamic properties of globular proteins from their atomic-level structure

7 April 2017

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Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure

7 April 2017

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Chemical approaches to the discovery and development of cancer therapies

28 September 2017

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Intramolecular quadruplex conformation of human telomeric DNA assessed with 125I-radioprobing

28 September 2017

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Low-energy circular dichroism of 2-aminopurine dinucleotide as a probe of local conformation of DNA and RNA.

28 September 2017

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Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer

28 September 2017

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Helix formation by guanylic acid

28 September 2017

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Platinum cross-linking of adenines and guanines on the quadruplex structures of the AG3(T2AG3)3 and (T2AG3)4 human telomere sequences in Na+ and K+ solutions

28 September 2017

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The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

28 September 2017

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Telomere maintenance as a target for anticancer drug discovery

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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DNA G-quadruplexes, telomere-specific proteins and telomere-associated enzymes as potential targets for new anticancer drugs

28 September 2017

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G-quadruplex DNA: a potential target for anti-cancer drug design

28 September 2017

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G-quadruplexes as targets for drug design

28 September 2017

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Targeting multi-stranded DNA structures

28 September 2017

1 reference

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Modern applications of analytical ultracentrifugation

28 September 2017

1 reference

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Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG).

28 September 2017

1 reference

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"...the tyranny of the lattice...".

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187823

Fluorescence studies of nucleotides and polynucleotides. I. Formycin, 2-aminopurine riboside, 2,6-diaminopurine riboside, and their derivatives.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187823

Telomere loss: mitotic clock or genetic time bomb?

28 September 2017

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Analysis of heterologous interacting systems by sedimentation velocity: curve fitting algorithms for estimation of sedimentation coefficients, equilibrium and kinetic constants

28 September 2017

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Crystal structure of four-stranded Oxytricha telomeric DNA

30 May 2018

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Effect of ions on the polymorphism, effective charge, and stability of human telomeric DNA. Photon correlation spectroscopy and circular dichroism studies.

30 May 2018

1 reference

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Fluorescence properties of 2-aminopurine in human telomeric DNA.

28 November 2018

1 reference

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2-Aminopurine electronic structure and fluorescence properties in DNA.

28 November 2018

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Strand orientation in the DNA quadruplex formed from the Oxytricha telomere repeat oligonucleotide d(G4T4G4) in solution.

28 November 2018

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The Bloom's syndrome helicase unwinds G4 DNA

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12 December 2020

Accelerated assembly of G-quadruplex structures by a small molecule

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Structure and stability of human telomeric sequence

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An Ambiguous Structure of a DNA 15-mer Thrombin Complex

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Porphyrins can catalyze the interconversion of DNA quadruplex structural types

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G-quadruplex DNA: a target for drug design

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Excitation energy transfer in DNA: duplex melting and transfer from normal bases to 2-aminopurine

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Identifiers

DOI

10.1093/NAR/GKI782

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16106044%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16106044%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

16106044

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16106044%20AND%20SRC:MED&resulttype=core&format=json