Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies (Q24810495)

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English	Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

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based on heuristic

inferred from title

drotrecogin alfa

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based on heuristic

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meningococcal disease

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based on heuristic

inferred from title

purpura fulminans

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based on heuristic

inferred from title

Jean-Louis Vincent

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object named as

Jean-Louis Vincent

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Europe PubMed Central

PubMed publication ID

5 July 2017

author name string

Simon Nadel

2

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Europe PubMed Central

PubMed publication ID

5 July 2017

Demetrios J Kutsogiannis

3

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Europe PubMed Central

PubMed publication ID

5 July 2017

R T Noel Gibney

4

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Europe PubMed Central

PubMed publication ID

5 July 2017

S Betty Yan

5

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Europe PubMed Central

PubMed publication ID

5 July 2017

Virginia L Wyss

6

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Europe PubMed Central

PubMed publication ID

5 July 2017

Joan E Bailey

7

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Europe PubMed Central

PubMed publication ID

5 July 2017

Carol L Mitchell

8

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Europe PubMed Central

PubMed publication ID

5 July 2017

Samiha Sarwat

9

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Europe PubMed Central

PubMed publication ID

5 July 2017

Stephen M Shinall

10

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Europe PubMed Central

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5 July 2017

Jonathan M Janes

11

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Europe PubMed Central

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5 July 2017

language of work or name

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publication date

17 May 2005

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Europe PubMed Central

PubMed publication ID

5 July 2017

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Europe PubMed Central

PubMed publication ID

5 July 2017

9

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Europe PubMed Central

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5 July 2017

4

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Europe PubMed Central

PubMed publication ID

5 July 2017

R331-43

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Europe PubMed Central

PubMed publication ID

5 July 2017

Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

7 April 2017

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

7 April 2017

The epidemiology of sepsis in the United States from 1979 through 2000

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

7 April 2017

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

7 April 2017

New method of classifying infections in critically ill patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Drug intervention trials in sepsis: divergent results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Developmental hemostasis: pro- and anticoagulant systems during childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Pathophysiology of meningococcal meningitis and septicaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial

1 reference

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28 September 2017

Such stuff as dreams are made on: mediator-directed therapy in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Inflammation and Coagulation: Implications for the Septic Patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Dexamethasone in adults with bacterial meningitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Coagulation inhibitors in the treatment of sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Meningococcal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

The epidemiology of the systemic inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Spontaneous intracerebral hemorrhage in critically ill patients: incidence over six years and associated factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Bacterial meningitis in the United States in 1995. Active Surveillance Team

1 reference

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28 September 2017

Hemorrhagic stroke as a complication of bacterial meningitis in adults: report of three cases and review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Acute bacterial meningitis in adults. A review of 493 episodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Epidemic meningococcemia and purpura fulminans with induced protein C deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 September 2017

Characteristics and immediate outcome of childhood meningitis treated in the pediatric intensive care unit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

30 May 2018

The epidemiology of severe sepsis in children in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

30 May 2018

Acute infectious purpura fulminans: pathogenesis and medical management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

30 May 2018

Acute bacterial meningitis in adults. A 20-year overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

30 May 2018

Cerebrovascular complications of bacterial meningitis in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

30 May 2018

Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Extended evaluation of recombinant human activated protein C United States Trial (ENHANCE US): a single-arm, phase 3B, multicenter study of drotrecogin alfa (activated) in severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Purpura fulminans due to Streptococcus pneumoniae sepsis following gastric bypass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

The neuropathology of septic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Activated protein C concentrate reverses purpura fulminans in severe genetic protein C deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Subarachnoid haemorrhage following activated protein C for bacterial meningitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Acute community-acquired bacterial meningitis in adults admitted to the intensive care unit: clinical manifestations, management and prognostic factors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

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28 November 2018

Combined antithrombin and protein C supplementation in meningococcal purpura fulminans: a pharmacokinetic study

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28 November 2018

Pneumococcal meningitis in adults: Spectrum of complications and prognostic factors in a series of 87 cases

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28 November 2018

Drotrecogin alfa (activated) for the treatment of meningococcal purpura fulminans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1269439

28 November 2018

Pneumococcal meningitis in the intensive care unit: prognostic factors of clinical outcome in a series of 80 cases

1 reference

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28 November 2018

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

1 reference

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28 November 2018

A 20-year epidemiological study of pneumococcal meningitis

1 reference

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28 November 2018

Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: a prospective double-blind study. J5 study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Community-acquired bacterial meningitis in adults: categorization of causes and timing of death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human recombinant activated protein C in meningococcal sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial meningitis in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated protein C for the treatment of fulminant meningococcal septicaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute bacterial meningitis: time for a better outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of recombinant tissue plasminogen activator in children with meningococcal purpura fulminans: A retrospective study*

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

PubMed publication ID

5 July 2017

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Europe PubMed Central

PubMed publication ID

5 July 2017

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Europe PubMed Central

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5 July 2017

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