Immunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implications (Q24798111)

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scientific article published on November 16, 2003

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English	Immunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implications	scientific article published on November 16, 2003

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Immunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implications (English)

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immunohistochemistry

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based on heuristic

inferred from title

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based on heuristic

inferred from title

1 reference

10.1186/1477-3163-2-8

https://api.crossref.org/works/10.1186/1477-3163-2-8

1 April 2024

3

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Michael Koch

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author name string

Anil Potti

1

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Rachel C. Hille

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617373

1 April 2024

language of work or name

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publication date

16 November 2003

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full work available at URL

http://carcinogenesis.com/images/pdf/JCarcinog_2003_2_1_8_42437.pdf

Portable Document Format

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617373

1 April 2024

https://europepmc.org/articles/PMC280698

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617373

1 April 2024

https://europepmc.org/articles/PMC280698?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617373

1 April 2024

Journal of Carcinogenesis

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2

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1

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8

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Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

7 April 2017

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

7 April 2017

Abnormal protein tyrosine kinase gene expression during melanoma progression and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

7 April 2017

Melanoma etiology: where are we?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

The HER-2/neu oncogene in tumors of the gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Melanoma genetics: an update with focus on the CDKN2A(p16)/ARF tumor suppressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Basic science of HER-2/neu: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Clinical and prognostic significance of the expression of the c-erbB-2 and c-erbB-3 oncoproteins in primary and metastatic malignant melanomas and breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Enforced c-KIT expression renders highly metastatic human melanoma cells susceptible to stem cell factor-induced apoptosis and inhibits their tumorigenic and metastatic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Sensitivity of HER-2/neu antibodies in archival tissue samples: potential source of error in immunohistochemical studies of oncogene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 September 2017

Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

30 May 2018

Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

30 May 2018

Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

30 May 2018

Correlation between encoded protein overexpression and copy number of the HER2 gene with survival in non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 November 2018

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280698

28 November 2018

Amplification and overexpression of HER-2/neu are uncommon in advanced stage melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel Mutations of the KIT (Mast/Stem Cell Growth Factor Receptor) Proto-Oncogene in Human Piebaldism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative immunohistochemical study of mammary and extramammary Paget's disease and superficial spreading melanoma, with particular emphasis on melanocytic markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of c-kit expression in cultured melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics and endometrial cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of Her-2/Neu status in breast carcinoma: comparative analysis of immunohistochemistry and fluorescent in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intertumoral heterogeneity of receptor-tyrosine kinases expression in human melanoma cell lines with different metastatic capabilities

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of tumor markers on breast and ovarian cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/14617373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1477-3163-2-8

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