Is there a role for Notch signalling in human breast cancer? (Q24795290)

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English	Is there a role for Notch signalling in human breast cancer?	scientific article

Statements

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scholarly article

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review article

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PubMed

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26 August 2020

title

Is there a role for Notch signalling in human breast cancer? (English)

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main subject

membrane protein

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PubMed

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15 December 2019

breast neoplasm

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PubMed

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26 August 2020

signal transduction

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PubMed

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26 August 2020

author name string

Keith Brennan

series ordinal

1

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Anthony M C Brown

series ordinal

2

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language of work or name

English

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publication date

20 January 2003

5 references

stated in

PubMed Central

retrieved

13 March 2019

stated in

PubMed Central

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3 April 2019

stated in

PubMed Central

retrieved

17 June 2019

stated in

PubMed Central

retrieved

15 December 2019

stated in

PubMed Central

retrieved

26 August 2020

published in

Breast Cancer Research

5 references

stated in

PubMed Central

retrieved

13 March 2019

stated in

PubMed Central

retrieved

3 April 2019

stated in

PubMed Central

retrieved

17 June 2019

stated in

PubMed Central

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15 December 2019

stated in

PubMed Central

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26 August 2020

volume

5

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issue

2

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page(s)

69-75

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cites work

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor

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Notch signaling induces cell cycle arrest in small cell lung cancer cells

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7 April 2017

Dll4, a novel Notch ligand expressed in arterial endothelium

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7 April 2017

Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion

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7 April 2017

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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PubMed Central

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7 April 2017

Wnt signaling and cancer

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7 April 2017

Notch signaling: cell fate control and signal integration in development

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7 April 2017

Control of endodermal endocrine development by Hes-1

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7 April 2017

Involvement of Notch1 in the development of mouse mammary tumors

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PubMed Central

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7 April 2017

Conservation of the Notch signalling pathway in mammalian neurogenesis

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PubMed Central

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7 April 2017

Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line

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PubMed Central

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7 April 2017

Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo

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PubMed Central

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7 April 2017

Notch signaling

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PubMed Central

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7 April 2017

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

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PubMed Central

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28 September 2017

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

EBNA2 and Notch signalling in Epstein-Barr virus mediated immortalization of B lymphocytes

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Activation of the Notch-regulated transcription factor CBF1/RBP-Jkappa through the 13SE1A oncoprotein

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

retrieved

28 September 2017

Molecular cloning of delta-4, a new mouse and human Notch ligand

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Imbalanced expression of TAN-1 and human Notch4 in endometrial cancers

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Notch signaling in the development of the inner ear: lessons from Drosophila

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Isolation and characterization of the notch ligand delta4.

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PubMed Central

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28 September 2017

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

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PubMed Central

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28 September 2017

Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus

1 reference

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PubMed Central

reference URL

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28 September 2017

Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture microdissection and cDNA arrays

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PubMed Central

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28 September 2017

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts.

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Notch signalling pathway and human diseases

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Notch signalling in Drosophila: three ways to use a pathway

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Notch inhibition of E47 supports the existence of a novel signaling pathway

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma

1 reference

stated in

PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Alterations in Notch signaling in neoplastic lesions of the human cervix

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 September 2017

Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors

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PubMed Central

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28 September 2017

Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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30 May 2018

The Ins and Outs of Notch Signaling

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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30 May 2018

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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30 May 2018

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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30 May 2018

The abruptex mutations of notch disrupt the establishment of proneural clusters in Drosophila.

1 reference

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Crossref

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https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

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Crossref

reference URL

https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

Repression by Notch is required before Wingless signalling during muscle progenitor cell development in Drosophila.

1 reference

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Crossref

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https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

Notch signaling targets the Wingless responsiveness of a Ubx visceral mesoderm enhancer in Drosophila.

1 reference

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Crossref

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https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

Expression of an activated Notch4(int-3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro.

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

Notch: a membrane-bound transcription factor.

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 November 2018

A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154142

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28 November 2018

Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1186%2FBCR559

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21 January 2018

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel association of a diverse range of genes with renal cell carcinoma as identified by differential display

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12631384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12631384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12631384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12631384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/BCR559

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Dimensions Publication ID

1023686219

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PMC publication ID

154142

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PubMed publication ID

12631384

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ResearchGate publication ID

10861838

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