Oxidative mechanism of arsenic toxicity and carcinogenesis (Q24704667)

12 December 2020

In vivo reduction of arsenate in mice and rabbits

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12 December 2020

Vascular effects of chronic arsenic exposure: a review

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12 December 2020

Arsenic trioxide inhibits growth of human T-cell leukaemia virus type I infected T-cell lines more effectively than retinoic acids

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12 December 2020

Arsenic can mediate skin neoplasia by chronic stimulation of keratinocyte-derived growth factors

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12 December 2020

Arsenical air pollution and lung cancer

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12 December 2020

Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes

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12 December 2020

Function and activation of NF-kappa B in the immune system

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12 December 2020

Arsenic mediates cell proliferation and gene expression in the bladder epithelium: association with activating protein-1 transactivation

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12 December 2020

Incidence of Transitional Cell Carcinoma and Arsenic in Drinking Water: A Follow-up Study of 8,102 Residents in an Arseniasis-endemic Area in Northeastern Taiwan

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12 December 2020

Arsenite stimulates poly(ADP-ribosylation) by generation of nitric oxide

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12 December 2020

Urinary inorganic arsenic and methylarsenic excretion following arsenate-rich seaweed ingestion (author's transl)

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12 December 2020

Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells

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12 December 2020

Is the genotoxic effect of arsenic mediated by oxygen free radicals?

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12 December 2020

Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways

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12 December 2020

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12 December 2020

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

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12 December 2020

Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells

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12 December 2020

Glutathione peroxidase and catalase modulate the genotoxicity of arsenite

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12 December 2020

Arsenic-induced oxidative stress and its reversibility following combined administration of N-acetylcysteine and meso 2,3-dimercaptosuccinic acid in rats

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12 December 2020

Dimethylarsinic acid, a main metabolite of inorganic arsenics, has tumorigenicity and progression effects in the pulmonary tumors of A/J mice

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12 December 2020

Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding

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12 December 2020

Induction of p53 protein expression by sodium arsenite

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12 December 2020

Arsenic species that cause release of iron from ferritin and generation of activated oxygen

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12 December 2020

Role of metabolism in arsenic toxicity

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12 December 2020

DNA damage by cadmium and arsenic salts assessed by the single cell gel electrophoresis assay

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12 December 2020

Arsenite induces DNA-protein crosslinks and cytokeratin expression in the WRL-68 human hepatic cell line

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12 December 2020

Inhibition of Renal Metabolism. Relative effects of arsenate on sodium, phosphate, and glucose transport by the rabbit proximal tubule

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12 December 2020

Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species

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12 December 2020

Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase

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12 December 2020

The interferon-beta and tamoxifen combination induces apoptosis using thioredoxin reductase

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12 December 2020

Hydrogen peroxide primes promonocytic U937 cells to produce IL-1 beta

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12 December 2020

Arsenite retards DNA break rejoining by inhibiting DNA ligation

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12 December 2020

Metabolism of inorganic arsenic (74As) in humans following oral ingestion

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12 December 2020

Low serum carotene level and increased risk of ischemic heart disease related to long-term arsenic exposure

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12 December 2020

Delay of the excision of UV light-induced DNA adducts is involved in the coclastogenicity of UV light plus arsenite

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12 December 2020

Metabolic methylation is a possible genotoxicity-enhancing process of inorganic arsenics.

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12 December 2020

ESR spin-trapping studies on the reaction of Fe2+ ions with H2O2-reactive species in oxygen toxicity in biology

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12 December 2020

Induction of gene amplification by arsenic

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12 December 2020

Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity

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12 December 2020

Inhibitors of endogenous nitrogen oxide formation block the promotion of neoplastic transformation in C3H 10T1/2 fibroblasts

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12 December 2020

Induction of lung-specific DNA damage by metabolically methylated arsenics via the production of free radicals

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12 December 2020

Skin cancer in chronic arsenicism

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12 December 2020

Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells

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12 December 2020

Mechanisms of arsenic-induced cell transformation

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12 December 2020

Effects on levels of glutathione and some related enzymes in tissues after an acute arsenic exposure in rats and their relationship to dietary protein deficiency

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12 December 2020

Arsenite enhances DNA double-strand breaks and cell killing of methyl methanesulfonate-treated cells by inhibiting the excision of alkali-labile sites

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12 December 2020

Placental arsenic and cadmium in relation to lipid peroxides and glutathione levels in maternal-infant pairs from a copper smelter area

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12 December 2020

Dose-dependent effects on tissue distribution and metabolism of dimethylarsinic acid in the mouse after intravenous administration

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12 December 2020

Arsenic-induced DNA-strand breaks associated with DNA-protein crosslinks in human fetal lung fibroblasts.

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12 December 2020

Stress proteins induced by arsenic.

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12 December 2020

Detection of superoxide radicals and peroxynitrite by 1-hydroxy-4-phosphonooxy-2,2,6,6-tetramethylpiperidine: quantification of extracellular superoxide radicals formation

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12 December 2020

Sodium arsenate induces overproduction of interleukin-1alpha in murine keratinocytes: role of mitochondria

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12 December 2020

The role of orally administered dimethylarsinic acid, a main metabolite of inorganic arsenics, in the promotion and progression of UVB-induced skin tumorigenesis in hairless mice

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12 December 2020

Cross-resistance to heavy metals in hydrogen peroxide-resistant CHO cell variants

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12 December 2020

Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

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12 December 2020

Relation between carcinogenesis, chromatin structure and poly(ADP-ribosylation) (review).

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12 December 2020

Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide

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12 December 2020

Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase

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12 December 2020

Induction of cystine transport in bovine pulmonary artery endothelial cells by sodium arsenite

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12 December 2020

Physiological functions of thioredoxin and thioredoxin reductase

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12 December 2020

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

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12 December 2020

Oral exposure of dimethylarsinic acid, a main metabolite of inorganic arsenics, in mice leads to an increase in 8-Oxo-2'-deoxyguanosine level, specifically in the target organs for arsenic carcinogenesis.

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12 December 2020

Comparative investigations of the genotoxic effects of metals in the single cells gel (SCG) assay and the sister chromatid exchange (SCE) test

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12 December 2020

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12 December 2020

Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite

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12 December 2020

Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production

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12 December 2020

Evaluation of the hydroxylamine Tempol-H as an in vivo radioprotector

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12 December 2020

Arsenite methylation by methylvitamin B12 and glutathione does not require an enzyme.

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12 December 2020

The speciation of the chemical forms of arsenic in the biological monitoring of exposure to inorganic arsenic

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12 December 2020

Opposite effect of NF-kB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite

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12 December 2020

Oral administration of dimethylarsinic acid, a main metabolite of inorganic arsenic, in mice promotes skin tumorigenesis initiated by dimethylbenz(a)anthracene with or without ultraviolet B as a promoter

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12 December 2020

The role of poly(ADP-ribose) metabolism in response to active oxygen cytotoxicity

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12 December 2020

Opposite biological effects of arsenic trioxide and arsacetin involve a different regulation of signaling in human gastric cancer MGC-803 cells

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12 December 2020

Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression

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12 December 2020

Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer.

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12 December 2020

Marked increase in bladder and lung cancer mortality in a region of Northern Chile due to arsenic in drinking water

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12 December 2020

Effect of orpiment (As2S3) on cytochrome P-450, glutathione and lipid peroxide levels of rat liver

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12 December 2020

Mechanism of comutagenesis of sodium arsenite with n-methyl-n-nitrosourea

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12 December 2020

The incidence of type 2 diabetes mellitus in Taiwan

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12 December 2020

Suppression of Fas ligand expression on endothelial cells by arsenite through reactive oxygen species

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12 December 2020

Heat shock response inhibits cytokine-inducible nitric oxide synthase expression in rat hepatocytes

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12 December 2020

Modulation of cellular antioxidant defense activities by sodium arsenite in human fibroblasts

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12 December 2020

The role of the redox protein thioredoxin in cell growth and cancer

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12 December 2020

Dose-response relationship between peripheral vascular disease and ingested inorganic arsenic among residents in blackfoot disease endemic villages in Taiwan.

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12 December 2020

Promotion of rat hepatocarcinogenesis by dimethylarsinic acid: association with elevated ornithine decarboxylase activity and formation of 8-hydroxydeoxyguanosine in the liver.

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12 December 2020

Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolite of inorganic arsenics, in mice

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12 December 2020

Arsenic ingestion and internal cancers: a review

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12 December 2020

Expression of iNOS in cultured rat pulmonary artery smooth muscle cells is inhibited by the heat shock response

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12 December 2020

Nitric oxide is involved in arsenite inhibition of pyrimidine dimer excision

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12 December 2020

Arsenic in drinking water and bladder cancer

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12 December 2020

Sodium arsenite enhances AP-1 and NFkappaB DNA binding and induces stress protein expression in precision-cut rat lung slices.

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12 December 2020

Lung cancer and arsenic exposure in drinking water: a case-control study in northern Chile

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12 December 2020

JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

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12 December 2020

Identification of dimethylarsinous and monomethylarsonous acids in human urine of the arsenic-affected areas in West Bengal, India.

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12 December 2020

Effects of glutathione on Fenton reagent-dependent radical production and DNA oxidation

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12 December 2020

Modulation of antioxidant responses by arsenic in maize

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12 December 2020

Hepatic damage caused by chronic arsenic toxicity in experimental animals

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12 December 2020

Effect of arsenic (V) on the antioxidant defense system: in vitro oxidation of rat plasma lipoprotein.

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12 December 2020

Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway

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12 December 2020

Interaction of arsenic(III) with nucleotide excision repair in UV-irradiated human fibroblasts

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12 December 2020

DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells

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12 December 2020

Apoptosis induced by arsenic trioxide in leukemia U937 cells is dependent on activation of p38, inactivation of ERK and the Ca2+-dependent production of superoxide

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12 December 2020

Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia

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12 December 2020

The role of oxidative DNA damage in human arsenic carcinogenesis: detection of 8-hydroxy-2'-deoxyguanosine in arsenic-related Bowen's disease.

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12 December 2020

NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells

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12 December 2020

Association of blood arsenic levels with increased reactive oxidants and decreased antioxidant capacity in a human population of northeastern Taiwan

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12 December 2020

Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis

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12 December 2020

Antioxidants inhibit activation of transcription factors and cytokine gene transcription in monocytes

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12 December 2020

Methylation study of a population environmentally exposed to arsenic in drinking water

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12 December 2020

Arsenite induces p53 accumulation through an ATM-dependent pathway in human fibroblasts

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12 December 2020

Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenics, is for the major part likely due to its peroxyl radical

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12 December 2020

The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase

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12 December 2020

Effects of arsenic, cadmium, chromium, and lead on gene expression regulated by a battery of 13 different promoters in recombinant HepG2 cells

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12 December 2020

Comparative studies of chromosomal aberration induced by trivalent and pentavalent arsenic

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12 December 2020

Promotion of NCI-Black-Reiter male rat bladder carcinogenesis by dimethylarsinic acid an organic arsenic compound.

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12 December 2020

Prevalence of skin cancer in an endemic area of chronic arsenicism in Taiwan

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12 December 2020

Effects of arsenite on p53, p21 and cyclin D expression in normal human fibroblasts -- a possible mechanism for arsenite's comutagenicity

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12 December 2020

Differential effects of luminol, nickel, and arsenite on the rejoining of ultraviolet light and alkylation-induced DNA breaks

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12 December 2020

Case-control study of bladder cancer and arsenic in drinking water

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12 December 2020

An insect model for assessing arsenic toxicity: arsenic elevated glutathione content in the Musca domestica and Trichoplusia ni.

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12 December 2020