A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles (Q24672583)

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English	A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles	scientific article

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title

A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles (English)

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author name string

P Fernandez-Salguero

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1

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S M Hoffman

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2

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S Cholerton

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3

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H Mohrenweiser

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4

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H Raunio

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5

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A Rautio

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6

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O Pelkonen

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7

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J D Huang

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8

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W E Evans

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9

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J R Idle

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10

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language of work or name

English

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publication date

September 1995

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published in

American Journal of Human Genetics

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volume

57

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issue

3

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page(s)

651-60

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cites work

Expression and alternative splicing of the cytochrome P-450 CYP2A7

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The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

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7 April 2017

Purification and characterization of human liver microsomal cytochrome P-450 2A6

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7 April 2017

Isolation and characterization of a cytochrome P450 of the IIA subfamily from human liver microsomes

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The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site

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Genetic basis for a lower prevalence of deficient CYP2D6 oxidative drug metabolism phenotypes in black Americans

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The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

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28 September 2017

Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons

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28 September 2017

A high-resolution, fluorescence-based, semiautomated method for DNA fingerprinting

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Role of gene duplication in evolution.

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Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

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Localization of CYP2F1 by multipoint linkage analysis and pulsed-field gel electrophoresis

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Human cytochromes P450: problems and prospects

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Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse

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30 May 2018

Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

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30 May 2018

Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide

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30 May 2018

Comparative metabolism of benzo[a]pyrene and drugs in human liver

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30 May 2018

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

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https://pubmed.ncbi.nlm.nih.gov/7668294

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of a novel thin-layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydroxycoumarin in human urine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7668294

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interindividual variability of coumarin 7-hydroxylation in healthy volunteers

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7668294

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1801261

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PubMed publication ID

7668294

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