Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP (Q24679086)

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G S Yap

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K Nguyen

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T A Gregorio

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L S Taylor

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B Eagleson

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L Secrest

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E A Southon

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S W Reid

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L Tessarollo

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M Bray

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D W McVicar

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K L Komschlies

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H A Young

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C A Biron

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A Sher

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G F Vande Woude

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

18 January 2000

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published in

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volume

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issue

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page(s)

751-5

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cites work

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7 April 2017

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Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

7 April 2017

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Specific antiviral activity demonstrated by TGTP, a member of a new family of interferon-induced GTPases

7 April 2017

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Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein

7 April 2017

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Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii

7 April 2017

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

28 September 2017

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Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

28 September 2017

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The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding

28 September 2017

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Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii

28 September 2017

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Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

28 September 2017

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Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration

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28 September 2017

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The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs

28 September 2017

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Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome

28 September 2017

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A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever

28 September 2017

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Role of interferon-gamma in murine cytomegalovirus infection

30 May 2018

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Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

30 May 2018

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In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10639151

12 December 2020

inferred from PubMed ID database lookup

Immune response in mice that lack the interferon-gamma receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10639151

12 December 2020

inferred from PubMed ID database lookup

Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10639151

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.97.2.751

1 reference

release_spnkooluvrcqziurzx2chxdpiy

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/spnkooluvrcqziurzx2chxdpiy

24 November 2022

mapped directly with Wikidata item

2200916

1 reference

1 reference

2200916

PubMed publication ID

10639151

1 reference