Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists (Q24677350)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14990676%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

title

Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14990676%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference

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24 November 2019

Trevor G Smart

1 reference

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24 November 2019

Uffe Kristiansen

1 reference

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24 November 2019

Bjarke Ebert

series ordinal

1 reference

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24 November 2019

Bente Frølund

series ordinal

1 reference

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24 November 2019

Povl Krogsgaard-Larsen

series ordinal

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24 November 2019

language of work or name

English

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publication date

27 February 2004

1 reference

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full work available at URL

24 November 2019

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665090

0 references

published in

Journal of Physiology

1 reference

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24 November 2019

volume

557

1 reference

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24 November 2019

issue

Pt 2

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24 November 2019

page(s)

389-413

1 reference

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

24 November 2019

cites work

1 reference

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Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human [...]

7 April 2017

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Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors

7 April 2017

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Structure and gating mechanism of the acetylcholine receptor pore

7 April 2017

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The quality of maximum likelihood estimates of ion channel rate constants

7 April 2017

1 reference

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Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits

28 September 2017

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Coupling of agonist binding to channel gating in the GABA(A) receptor

28 September 2017

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Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors.

28 September 2017

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Subunit composition, distribution and function of GABA(A) receptor subtypes

28 September 2017

1 reference

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Drug interactions at GABA(A) receptors

28 September 2017

1 reference

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Dominant gating governing transient GABA(A) receptor activity: a first latency and Po/o analysis.

28 September 2017

1 reference

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Bioisosteric determinants for subtype selectivity of ligands for heteromeric GABA(A) receptors.

28 September 2017

1 reference

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Constructing inhibitory synapses

28 September 2017

1 reference

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Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Arginine residue 120 of the human GABAA receptor alpha 1, subunit is essential for GABA binding and chloride ion current gating

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Pharmacological and physiological characterization of murine homomeric beta3 GABA(A) receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Hippocampal GABAAchannel conductance increased by diazepam

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Stoichiometry and assembly of a recombinant GABAA receptor subtype.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

From ion currents to genomic analysis: recent advances in GABAA receptor research.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

GABA synaptic mechanisms: stereochemical and conformational requirements

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Electrophysiological studies of the GABAA receptor ligand, 4-PIOL, on cultured hippocampal neurones

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Whole-cell and single-channel recordings of GABA-gated currents in cultured chick cerebral neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Pentobarbital modulates gamma-aminobutyric acid-activated single-channel conductance in rat cultured hippocampal neurons

30 May 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

30 May 2018

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

7 January 2021

inferred from DOI database lookup

GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Spontaneous and GABA-induced single channel currents in cultured murine spinal cord neurons.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

A novel modulatory binding site for zinc on the GABAA receptor complex in cultured rat neurones

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Subunit arrangement of gamma-aminobutyric acid type A receptors

30 May 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Interaction at End-Plate Receptors between Different Choline Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Two conserved arginines in the extracellular N-terminal domain of the GABA(A) receptor alpha(5) subunit are crucial for receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Desensitized states prolong GABAA channel responses to brief agonist pulses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Activation of subconductance states by ?-aminobutyric acid and its analogs in chick cerebral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Stochastic Properties of Ion Channel Openings and Bursts in a Membrane Patch that Contains Two Channels: Evidence Concerning the Number of Channels Present when a Record Containing Only Single Openings is Observed

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Identification of a [3H]muscimol photoaffinity substrate in the bovine gamma-aminobutyric acidA receptor alpha subunit.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665090

Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA

28 November 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.054734

Molecular orbital studies on the conformation of gamma-aminobutyric acid and muscimol

21 January 2018

1 reference

12 December 2020

GABA Analogues Activate Channels of Different Duration on Cultured Mouse Spinal Neurons

1 reference

12 December 2020

Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons

1 reference

12 December 2020

Structural factors governing agonist and antagonist activity in the GABAA system

1 reference

12 December 2020

Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

1 reference

12 December 2020

Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single- channel properties

1 reference

12 December 2020

The low efficacy gamma-aminobutyric acid type A agonist 5-(4-piperidyl)isoxazol-3-ol opens brief Cl- channels in embryonic rat olfactory bulb neurons

1 reference

12 December 2020

10.1113/JPHYSIOL.2003.054734

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14990676%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

PMC publication ID

1665090

0 references

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14990676%20AND%20SRC:MED&resulttype=core&format=json