STING is a direct innate immune sensor of cyclic di-GMP (Q24633648)

GOA release 2020-03-11

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Mamoru Hyodo

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Dara L Burdette

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Kathryn M Monroe

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Katia Sotelo-Troha

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Jeff S Iwig

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Barbara Eckert

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Yoshihiro Hayakawa

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Russell E Vance

IFI16 is an innate immune sensor for intracellular DNA

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language of work or name

English

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publication date

27 October 2011

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published in

Nature

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volume

478

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issue

7370

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page(s)

515-8

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203314

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

7 April 2017

1 reference

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A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

7 April 2017

1 reference

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

7 April 2017

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

7 April 2017

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ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

7 April 2017

1 reference

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

7 April 2017

1 reference

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203314

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203314

Roles of cyclic diguanylate in the regulation of bacterial pathogenesis

7 April 2017

1 reference

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Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates

7 April 2017

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Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203314

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203314

Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence

7 April 2017

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Approaching the asymptote? Evolution and revolution in immunology

7 April 2017

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

7 April 2017

1 reference

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Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

7 April 2017

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The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides

27 September 2017

1 reference

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The potential of 3',5'-cyclic diguanylic acid (c-di-GMP) as an effective vaccine adjuvant

27 September 2017

1 reference

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MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals

27 September 2017

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A role for the EAL-like protein STM1344 in regulation of CsgD expression and motility in Salmonella enterica serovar Typhimurium

27 September 2017

1 reference

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UV crosslinking of proteins to nucleic acids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203314

Bacterial c-di-GMP is an immunostimulatory molecule

28 November 2018

1 reference

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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

28 November 2018

1 reference

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The second messenger bis-(3'-5')-cyclic-GMP and its PilZ domain-containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21947006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10429

1 reference

Dimensions Publication ID

1012079432

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1 reference

1 reference

PubMed publication ID

21947006

1 reference