Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes (Q24623828)

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5 February 2020

title

Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes (English)

1 reference

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5 February 2020

1 reference

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5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20534556%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Yihua Chen

1 reference

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5 February 2020

Ben Shen

series ordinal

1 reference

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5 February 2020

language of work or name

English

0 references

publication date

7 June 2010

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

5 February 2020

published in

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5 February 2020

volume

107

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5 February 2020

issue

1 reference

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5 February 2020

page(s)

11331-11335

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Structure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne Biosynthesis

5 February 2020

cites work

1 reference

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The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases

7 April 2017

1 reference

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Antitumor antibiotics: bleomycin, enediynes, and mitomycin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

The calicheamicin gene cluster and its iterative type I enediyne PKS

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Calicheamicins, a novel family of antitumor antibiotics: taxonomy, fermentation and biological properties

7 April 2017

1 reference

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Characterization of the SgcF epoxide hydrolase supporting an (R)-vicinal diol intermediate for enediyne antitumor antibiotic C-1027 biosynthesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Biosynthesis of enediyne antitumor antibiotics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Single chemical modifications of the C-1027 enediyne core, a radiomimetic antitumor drug, affect both drug potency and the role of ataxia-telangiectasia mutated in cellular responses to DNA double-strand breaks

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Mylotarg: antibody-targeted chemotherapy comes of age.

27 September 2017

1 reference

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SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Products of the iterative polyketide synthases in 9- and 10-membered enediyne biosynthesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895059

Iterative type I polyketide synthases for enediyne core biosynthesis.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1003442107

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1003442107

Biosynthesis of the enediyne antitumor antibiotic C-1027

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20534556

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Recombinant polyketide synthesis in Streptomyces: engineering of improved host strains

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20534556

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20534556

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1003442107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20534556%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

ADS bibcode

2010PNAS..10711331H

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20534556%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

20534556

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20534556%20AND%20SRC:MED&resulttype=core&format=json