Single-gene mutations and healthy ageing in mammals (Q24629563)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Suppression of aging in mice by the hormone Klotho

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

A potential link between phosphate and aging--lessons from Klotho-deficient mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

A C. elegans mutant that lives twice as long as wild type

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Genetic pathways that regulate ageing in model organisms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Comparative longevity of pet dogs and humans: implications for gerontology research

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

7 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Extension of murine life span by overexpression of catalase targeted to mitochondria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Extended longevity in mice lacking the insulin receptor in adipose tissue

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

The p66shc adaptor protein controls oxidative stress response and life span in mammals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

The endocrine regulation of aging by insulin-like signals

7 April 2017

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Longevity in mice: is stress resistance a common factor?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Disruption of protein kinase A in mice enhances healthy aging.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Lifespan extension in genetically modified mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Mechanisms of stress resistance in Snell dwarf mouse fibroblasts: enhanced antioxidant and DNA base excision repair capacity, but no differences in mitochondrial metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Long-lived ames dwarf mice are resistant to chemical stressors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

The somatotropic axis and aging: mechanisms and persistent questions about practical implications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Insulin sensitivity as a key mediator of growth hormone actions on longevity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Telomerase reverse transcriptase delays aging in cancer-resistant mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Adiponectin levels and genotype: a potential regulator of life span in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Functionally significant insulin-like growth factor I receptor mutations in centenarians

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

FOXO transcription factors in ageing and cancer.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Endocrine regulation of ageing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Brain IRS2 signaling coordinates life span and nutrient homeostasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Evolutionary conservation of regulated longevity assurance mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Transgenic mice with a reduced core body temperature have an increased life span

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Regulation of oxidative stress by the anti-aging hormone klotho

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

The consequences of altered somatotropic system on reproduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Is height related to longevity?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Congenital growth hormone (GH) deficiency and atherosclerosis: effects of GH replacement in GH-naive adults

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Thyroid status, disability and cognitive function, and survival in old age.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Long-lived lines of Caenorhabditis elegans can be used to establish predictive biomarkers of aging

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Dwarf mice and the ageing process.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span

19 June 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Multiplex stress resistance in cells from long-lived dwarf mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Comparing adiposity profiles in three mouse models with altered GH signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Impact of reduced insulin-like growth factor-1/insulin signaling on aging in mammals: novel findings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Big mice die young: early life body weight predicts longevity in genetically heterogeneous mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Induction of endogenous insulin-like growth factor-I secretion alters the hypothalamic-pituitary-testicular function in growth hormone-deficient adult dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Diabetes. Causes of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Demographic and clinical characteristics of geriatric horses: 467 cases (1989-1999).

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Reduced insulin/IGF-1 signalling and human longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0281

Delayed ageing through damage protection by the Arf/p53 pathway

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Longer life spans and delayed maturation in wild-derived mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001310

Type 5 adenylyl cyclase disruption increases longevity and protects against stress

28 November 2018

1 reference

12 December 2020

Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis"

1 reference

12 December 2020

Loss of pregnancy-associated plasma protein A extends lifespan in mice

1 reference

12 December 2020

Growth negatively impacts the life span of mammals

1 reference

12 December 2020

Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice

1 reference

12 December 2020

Adipocytokines and lipid levels in Ames dwarf and calorie-restricted mice

1 reference

12 December 2020

Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria

1 reference

12 December 2020

Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity

1 reference

12 December 2020

Articular aging and osteoarthrosis in dwarf mice

1 reference

12 December 2020

Patients with congenital deficiency of IGF-I seem protected from the development of malignancies: A preliminary report

1 reference

12 December 2020