Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism (Q24613339)

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12 February 2020

title

Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism (English)

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1 reference

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12 February 2020

Derek Erion

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12 February 2020

Rudolph Beiler

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12 February 2020

Zhong-Wu Liu

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12 February 2020

Jeffrey Zigman

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12 February 2020

John D Elsworth

1 reference

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12 February 2020

Joseph M Savitt

1 reference

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12 February 2020

Richard DiMarchi

1 reference

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12 February 2020

Matthias Tschoep

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12 February 2020

Robert H Roth

1 reference

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12 February 2020

Xiao-Bing Gao

1 reference

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12 February 2020

Tamas L Horvath

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12 February 2020

language of work or name

English

0 references

publication date

1 November 2009

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12 February 2020

published in

Journal of Neuroscience

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12 February 2020

volume

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12 February 2020

issue

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12 February 2020

page(s)

14057-14065

1 reference

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The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

12 February 2020

cites work

1 reference

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Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

7 April 2017

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Ghrelin controls hippocampal spine synapse density and memory performance

7 April 2017

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7 April 2017

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Mice lacking ghrelin receptors resist the development of diet-induced obesity

7 April 2017

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

7 April 2017

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Superoxide activates mitochondrial uncoupling proteins

7 April 2017

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Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice

7 April 2017

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Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference

7 April 2017

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Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

7 April 2017

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Ghrelin induces adiposity in rodents

7 April 2017

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7 April 2017

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Ghrelin antagonized 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells

27 September 2017

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Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons

27 September 2017

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Regulation of hypothalamic malonyl-CoA by central glucose and leptin.

27 September 2017

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Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens

27 September 2017

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Body weight in patients with Parkinson's disease

27 September 2017

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Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: implications for its involvement in brain reward

27 September 2017

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Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia

27 September 2017

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Expanding insights of mitochondrial dysfunction in Parkinson's disease.

27 September 2017

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Expression of ghrelin receptor mRNA in the rat and the mouse brain

27 September 2017

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27 September 2017

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Calorie restriction, SIRT1 and metabolism: understanding longevity

27 September 2017

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Long-chain fatty acids increase cellular dopamine in an immortalized cell line (MN9D) derived from mouse mesencephalon.

27 September 2017

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Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease

27 September 2017

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27 September 2017

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Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans.

27 September 2017

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27 September 2017

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UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

27 September 2017

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Opioids excite dopamine neurons by hyperpolarization of local interneurons

30 May 2018

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Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra

30 May 2018

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28 November 2018

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Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation

28 November 2018

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Bcl-x is required for proper development of the mouse substantia nigra.

28 November 2018

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Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity

28 November 2018

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Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity

28 November 2018

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Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.

28 November 2018

1 reference

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Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning.

28 November 2018

1 reference

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The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

28 November 2018

1 reference

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Circulating ghrelin levels are decreased in human obesity.

28 November 2018

1 reference

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Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease

28 November 2018

1 reference

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[Depression in Parkinson's disease. Part 1: epidemiology, signs and symptoms, pathophysiology and diagnosis]

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19906954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Body mass index and the risk of Parkinson disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19906954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.3890-09.2009

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906954%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906954%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19906954

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906954%20AND%20SRC:MED&resulttype=core&format=json