A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent models (Q24612184)

0 references

Kristina K Wolf

0 references

Arlene S Bridges

0 references

J Scott Eaddy

0 references

C Lisa Kurtz

0 references

J Ed Hall

0 references

Mary F Paine

0 references

Richard R Tidwell

0 references

Paul B Watkins

0 references

language of work or name

English

0 references

publication date

December 2012

0 references

published in

Toxicological Sciences

1 reference

A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2

PubMed

volume

130

0 references

issue

0 references

page(s)

416-26

0 references

cites work

1 reference

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Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

7 April 2017

1 reference

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Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Renal cholesterol accumulation: a durable response after acute and subacute renal insults

7 April 2017

1 reference

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Tissue Kim-1 and urinary clusterin as early indicators of cisplatin-induced acute kidney injury in rats

7 April 2017

1 reference

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The nuclear genes Mtfr1 and Dufd1 regulate mitochondrial dynamic and cellular respiration

7 April 2017

1 reference

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Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells

7 April 2017

1 reference

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Neglected tropical diseases and the millennium development goals: why the "other diseases" matter: reality versus rhetoric

7 April 2017

1 reference

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Acute unilateral ischemic renal injury induces progressive renal inflammation, lipid accumulation, histone modification, and "end-stage" kidney disease

27 September 2017

1 reference

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Sulfatide-reactive natural killer T cells abrogate ischemia-reperfusion injury

27 September 2017

1 reference

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Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice

27 September 2017

1 reference

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Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity

27 September 2017

1 reference

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Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass

27 September 2017

1 reference

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Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel

27 September 2017

1 reference

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Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Efficient control of population structure in model organism association mapping

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate

27 September 2017

1 reference

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The activation and physiological functions of the proprotein convertases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Genomewide association analysis in diverse inbred mice: power and population structure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Drugs and drug resistance in African trypanosomiasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Efficacy of DB289 in Thai patients with Plasmodium vivax or acute, uncomplicated Plasmodium falciparum infections

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Renal tubular triglyercide accumulation following endotoxic, toxic, and ischemic injury.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Dicationic diarylfurans as anti-Pneumocystis carinii agents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

Hepatic gene expression changes throughout the day in the Fischer rat: implications for toxicogenomic experiments.

27 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS238

Triglyceride accumulation in injured renal tubular cells: alterations in both synthetic and catabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS238

Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS238

Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS238

Unusual dehydroxylation of antimicrobial amidoxime prodrugs by cytochrome b5 and NADH cytochrome b5 reductase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498743

The Mouse Phenome Project

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22940726

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired expression of genes coding for reactive oxygen species scavenging enzymes in testes of Mtfr1/Chppr-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22940726

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/TOXSCI/KFS238

0 references

Fatcat ID

release_js7mqlin7fba5iukzo2wxtliwe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/js7mqlin7fba5iukzo2wxtliwe