Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome (Q24611264)

object named as

Daniella C Bartholomeu

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Douglas T Golenbock

object named as

Douglas T Golenbock

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author name string

Shruti Sharma

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Rosane B DeOliveira

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Parisa Kalantari

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Peggy Parroche

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Nadege Goutagny

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Zhaozhao Jiang

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Jennie Chan

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Fanny Lauw

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J Perry Hall

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Glen N Barber

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Katherine A Fitzgerald

Peroxisomes are signaling platforms for antiviral innate immunity

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language of work or name

English

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publication date

26 August 2011

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194-207

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cites work

1 reference

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Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

7 April 2017

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Activation of innate immune antiviral responses by Nod2

7 April 2017

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

7 April 2017

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

7 April 2017

1 reference

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

7 April 2017

1 reference

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

7 April 2017

1 reference

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

7 April 2017

1 reference

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

7 April 2017

1 reference

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

7 April 2017

1 reference

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

7 April 2017

1 reference

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

7 April 2017

1 reference

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Genome sequence of the human malaria parasite Plasmodium falciparum

7 April 2017

1 reference

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Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

7 April 2017

1 reference

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Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein

7 April 2017

1 reference

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An Atomic Model of the Interferon-β Enhanceosome

7 April 2017

1 reference

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

7 April 2017

1 reference

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Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria

7 April 2017

1 reference

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

7 April 2017

1 reference

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A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

7 April 2017

1 reference

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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma

27 September 2017

1 reference

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Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

IFNGR1 polymorphisms in Thai malaria patients

27 September 2017

1 reference

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Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Malarial hemozoin is a Nalp3 inflammasome activating danger signal

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A

27 September 2017

1 reference

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Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.

27 September 2017

1 reference

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RNA recognition and signal transduction by RIG-I-like receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.

27 September 2017

1 reference

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A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Murine cerebral malaria development is independent of toll-like receptor signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Differential gene induction by type I and type II interferons and their combination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Type I interferon production enhances susceptibility to Listeria monocytogenes infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Pathogenesis of malaria and clinically similar conditions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Classical CD11c+ dendritic cells, not plasmacytoid dendritic cells, induce T cell responses to Plasmodium chabaudi malaria

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

28 November 2018

1 reference

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MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.

28 November 2018

1 reference

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Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Cutting edge: conventional dendritic cells are the critical APC required for the induction of experimental cerebral malaria

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Strong immunostimulatory activity of AT-oligodeoxynucleotide requires a six-base loop with a self-stabilized 5'-C...G-3' stem structure.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Interferon-alpha receptor-1 (IFNAR1) variants are associated with protection against cerebral malaria in the Gambia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

IFNGR1 gene promoter polymorphisms and susceptibility to cerebral malaria

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162998

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: the requirement of extracellular signal-regulated kinase, p38, c-Jun N-terminal kinase and NF-kappaB pathways for the expression of

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21820332

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IFI16 is an innate immune sensor for intracellular DNA

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.IMMUNI.2011.05.016

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.IMMUNI.2011.05.016

1 reference

1 reference

1 reference

PubMed publication ID

21820332

1 reference