Small-molecule inhibition of BRDT for male contraception (Q24616901)

21 June 2017

title

Small-molecule inhibition of BRDT for male contraception (English)

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21 June 2017

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Panagis Filippakopoulos

object named as

Panagis Filippakopoulos

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Madeleine Lemieux

object named as

Madeleine E Lemieux

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21 June 2017

Stefan Knapp

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Sarah Picaud

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21 June 2017

Martin M Matzuk

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21 June 2017

Michael R McKeown

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21 June 2017

Qinglei Li

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21 June 2017

Lang Ma

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21 June 2017

Julio E Agno

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21 June 2017

Richard N Yu

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21 June 2017

Jun Qi

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21 June 2017

James E Bradner

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21 June 2017

language of work or name

English

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publication date

1 August 2012

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21 June 2017

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21 June 2017

volume

150

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21 June 2017

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21 June 2017

page(s)

673-684

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Selective inhibition of BET bromodomains

21 June 2017

cites work

1 reference

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Absence of tektin 4 causes asthenozoospermia and subfertility in male mice

7 April 2017

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A distinct cyclin A is expressed in germ cells in the mouse

7 April 2017

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GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline

7 April 2017

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The first bromodomain of Brdt, a testis-specific member of the BET sub-family of double-bromodomain-containing proteins, is essential for male germ cell differentiation

7 April 2017

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Loss of zona pellucida binding proteins in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis

7 April 2017

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Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility

7 April 2017

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Plzf is required in adult male germ cells for stem cell self-renewal

7 April 2017

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Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein

7 April 2017

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Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

7 April 2017

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7 April 2017

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The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

7 April 2017

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Nucleoprotein transitions during spermiogenesis in mice with transition nuclear protein Tnp1 and Tnp2 mutations

7 April 2017

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The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background

10 May 2017

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Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent

27 September 2017

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The Aurora Kinase C c.144delC mutation causes meiosis I arrest in men and is frequent in the North African population

27 September 2017

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The biology of infertility: research advances and clinical challenges

27 September 2017

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Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes

27 September 2017

1 reference

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Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2.

27 September 2017

1 reference

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Identification and characterization of BRDT: A testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Identification of a novel isoform of poly(A) polymerase, TPAP, specifically present in the cytoplasm of spermatogenic cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Murine polo like kinase 1 gene is expressed in meiotic testicular germ cells and oocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Specific expression of nuclear proto-oncogenes before entry into meiotic prophase of spermatogenesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Identification of unique, differentiation stage-specific patterns of expression of the bromodomain-containing genes Brd2, Brd3, Brd4, and Brdt in the mouse testis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420011

Translational regulation and deadenylation of a protamine mRNA during spermiogenesis in the mouse

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22901802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2012.06.045

1 reference

OpenCitations bibliographic resource ID

21 June 2017

1424417

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1424417

1 reference