Structural basis for engagement by complement factor H of C3b on a self surface (Q24604385)

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22 January 2020

title

Structural basis for engagement by complement factor H of C3b on a self surface (English)

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22 January 2020

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22 January 2020

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22 January 2020

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22 January 2020

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22 January 2020

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22 January 2020

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22 January 2020

Paul N Barlow

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22 January 2020

Hugh P Morgan

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22 January 2020

Christoph Q Schmidt

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22 January 2020

Mara Guariento

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22 January 2020

Dominic Gillespie

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22 January 2020

Conny M Johansson

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22 January 2020

Dušan Uhrín

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22 January 2020

language of work or name

English

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publication date

13 February 2011

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Nature Structural & Molecular Biology

22 January 2020

published in

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volume

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issue

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22 January 2020

page(s)

463-470

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The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Structural basis for complement factor H linked age-related macular degeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Complement factor H polymorphism in age-related macular degeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Electrostatics of nanosystems: application to microtubules and the ribosome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Control of the amplification convertase of complement by the plasma protein beta1H

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Associative and structural properties of the region of complement factor H encompassing the Tyr402His disease-related polymorphism and its interactions with heparin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

A structural basis for complement inhibition by Staphylococcus aureus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modelling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Structure of complement receptor 2 in complex with its C3d ligand

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Solution structure of a pair of complement modules by nuclear magnetic resonance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Phasercrystallographic software

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Scaling and assessment of data quality

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Coot: model-building tools for molecular graphics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Refinement of macromolecular structures by the maximum-likelihood method

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

A new map of glycosaminoglycan and C3b binding sites on factor H

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Structure of C3b reveals conformational changes that underlie complement activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Disease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Host recognition and target differentiation by factor H, a regulator of the alternative pathway of complement

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Solution structure of the fifth repeat of factor H: a second example of the complement control protein module

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Complement: a key system for immune surveillance and homeostasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Mutations of factor H impair regulation of surface-bound C3b by three mechanisms in atypical hemolytic uremic syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Cutting edge: members of the Staphylococcus aureus extracellular fibrinogen-binding protein family inhibit the interaction of C3d with complement receptor 2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Cutting edge: localization of the host recognition functions of complement factor H at the carboxyl-terminal: implications for hemolytic uremic syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Protein-ligand interactions: exchange processes and determination of ligand conformation and protein-ligand contacts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

Modulation of the alternative complement pathways by beta 1 H globulin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512577

The electrostatic nature of C3d-complement receptor 2 association.

27 September 2017

1 reference

Isolating the Epstein-Barr virus gp350/220 binding site on complement receptor type 2 (CR2/CD21).

21 January 2018

1 reference

NMR Analysis of Interacting Soluble Forms of the Cell−Cell Recognition Molecules CD2 and CD48†

21 January 2018

1 reference

Partial characterization of human complement factor H by protein and cDNA sequencing: homology with other complement and non-complement proteins

21 January 2018

1 reference

Regulation of alternative pathway complement activation by glycosaminoglycans: specificity of the polyanion binding site on factor H

31 March 2020

1 reference

Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome

31 March 2020

1 reference

Critical role of the C-terminal domains of factor H in regulating complement activation at cell surfaces

31 March 2020

1 reference

New effort to develop molecular tools for early cancer detection under way

31 March 2020

1 reference

The C-terminus of complement regulator Factor H mediates target recognition: evidence for a compact conformation of the native protein

31 March 2020

1 reference

Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking

31 March 2020

1 reference

Identification of the second heparin-binding domain in human complement factor H

31 March 2020

1 reference

12 December 2020

Gene discovery provides clues to cause of age-related macular degeneration

1 reference

12 December 2020

Identification of a heparin binding domain in the seventh short consensus repeat of complement factor H

1 reference

12 December 2020

Identification of complement regulatory domains in human factor H

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.2018

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21317894%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 January 2020

1001297380

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Fatcat ID

release_pnhednqiwveslj2uazcbsiizpq

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Fatcat

https://api.fatcat.wiki/v0/release/pnhednqiwveslj2uazcbsiizpq

24 November 2022

mapped directly with Wikidata item

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2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21317894%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21317894

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21317894%20AND%20SRC:MED&resulttype=core&format=json