Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype (Q24561448)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

30 November 2024

G D Plowman

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P. W. Cook

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

30 November 2024

M. Piepkorn

1 reference

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30 November 2024

C. H. Clegg

1 reference

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30 November 2024

J. M. DeMay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

30 November 2024

J. R. Brown

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

30 November 2024

M. R. Pittelkow

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

full work available at URL

30 November 2024

language of work or name

English

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publication date

1 November 1997

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http://www.jci.org/articles/view/119766/files/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

https://europepmc.org/articles/PMC508424

30 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

https://europepmc.org/articles/PMC508424?pdf=render

30 November 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9410906

http://www.jci.org/articles/view/119766/files/pdf

30 November 2024

1 reference

https://api.crossref.org/works/10.1172/JCI119766

Journal of Clinical Investigation

30 November 2024

published in

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volume

100

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issue

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page(s)

2286-94

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cites work

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Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7

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Structure and function of human amphiregulin: a member of the epidermal growth factor family

24 March 2017

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The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity

24 March 2017

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A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin

24 March 2017

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Epidermal growth factor/transforming growth factor alpha receptors and psoriasis

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Heparin-binding ligands mediate autocrine epidermal growth factor receptor activation In skin organ culture

27 September 2017

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Dermal injection of immunocytes induces psoriasis

27 September 2017

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Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions

27 September 2017

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Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes. Evidence that IL-1-inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease

27 September 2017

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Topical therapy for psoriasis.

27 September 2017

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Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis

27 September 2017

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Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes

27 September 2017

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Human hair growth in vitro: a model for the study of hair follicle biology

27 September 2017

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Schwannoma-derived growth factor must be transported into the nucleus to exert its mitogenic activity.

27 September 2017

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Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice

27 September 2017

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Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinoc

27 September 2017

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Keratinocyte expression of B7-1 in transgenic mice amplifies the primary immune response to cutaneous antigens.

27 September 2017

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Epidermal expression of intercellular adhesion molecule 1 is not a primary inducer of cutaneous inflammation in transgenic mice

27 September 2017

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Expression of amphiregulin is regulated in cultured human keratinocytes and in developing fetal skin

27 September 2017

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Psoriatic alopecia manifestation, course and therapy in 34 patients

27 September 2017

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Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

27 September 2017

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Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein

27 September 2017

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Resolution of immune-mediated diseases following allogeneic bone marrow transplantation for leukaemia

27 September 2017

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Psoriatic alopecia: acute and chronic hair loss in 47 patients with scalp psoriasis

27 September 2017

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Tacrolimus (FK 506)--a new therapeutic agent for severe recalcitrant psoriasis

27 September 2017

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Interleukin 6: insights to its function in skin by overexpression in transgenic mice

27 September 2017

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Cyclosporine in the treatment of dermatologic disease: an update

27 September 2017

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Amphiregulin-dependent proliferation of cultured human keratinocytes: autocrine growth, the effects of exogenous recombinant cytokine, and apparent requirement for heparin-like glycosaminoglycans

27 September 2017

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Overexpression of amphiregulin, a major autocrine growth factor for cultured human keratinocytes, in hyperproliferative skin diseases

27 September 2017

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Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

30 May 2018

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Programming gene expression in developing epidermis

30 May 2018

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Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation

30 May 2018

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Growth factor-independent proliferation of normal human neonatal keratinocytes: production of autocrine- and paracrine-acting mitogenic factors

30 May 2018

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Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

30 May 2018

1 reference

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The hair root pattern in psoriasis of the scalp

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508424

Murine psoriasis-like disorder induced by naive CD4+ T cells.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508424

Methotrexate therapy of psoriasis: differential sensitivity of proliferating lymphoid and epithelial cells to the cytotoxic and growth-inhibitory effects of methotrexate

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508424

Carboxyl-terminal truncation of leucine76 converts heparin-binding EGF-like growth factor from a heparin-enhancible to a heparin-suppressible growth factor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508424

A morphometric and histologic study of the scalp in psoriasis. Paradoxical sebaceous gland atrophy and decreased hair shaft diameters without alopecia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508424

Psoriasis after allogeneic bone marrow transplantation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508424

28 November 2018

1 reference

12 December 2020

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

1 reference

12 December 2020

Differential effects of a heparin antagonist (hexadimethrine) or chlorate on amphiregulin, basic fibroblast growth factor, and heparin-binding EGF-like growth factor activity.

1 reference

12 December 2020

[Resolution of psoriasis vulgaris following allogeneic bone marrow transplantation for aplastic anemia]

1 reference

12 December 2020

Advances in psoriasis therapy

1 reference

12 December 2020

Amphiregulin and nerve growth factor expression are regulated by barrier status in murine epidermis

1 reference

12 December 2020

Transgenic Mice Expressing IFN-γ in the Epidermis Have Eczema, Hair Hypopigmentation, and Hair Loss

1 reference

12 December 2020

Overexpression of transforming growth factor alpha in psoriatic epidermis

1 reference

12 December 2020

Growth of normal human keratinocytes and fibroblasts in serum-free medium is stimulated by acidic and basic fibroblast growth factor

1 reference

12 December 2020

Scarring alopecia in psoriasis

1 reference

12 December 2020

Response to and expression of amphiregulin by ovarian carcinoma and normal ovarian surface epithelial cells: nuclear localization of endogenous amphiregulin

1 reference

12 December 2020

Modulation of epidermal growth factor receptors in psoriatic lesions during treatment with topical EGF

1 reference

12 December 2020

Inhibition of autonomous human keratinocyte proliferation and amphiregulin mitogenic activity by sulfated polysaccharides

1 reference

12 December 2020

Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas

1 reference

12 December 2020

Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice

1 reference

12 December 2020

Autonomous growth of human keratinocytes requires epidermal growth factor receptor occupancy

1 reference

12 December 2020

Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas

1 reference

12 December 2020