Searching sequence space for protein catalysts (Q24555209)

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K U Walter

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P Kast

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D Hilvert

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

11 September 2001

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published in

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volume

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issue

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page(s)

10596-601

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cites work

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Sequence space, folding and protein design

24 March 2017

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Probing the role of the C-terminus of Bacillus subtilis chorismate mutase by a novel random protein-termination strategy

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De novo design of helical bundles as models for understanding protein folding and function.

27 September 2017

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27 September 2017

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Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

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Probing enzyme quaternary structure by combinatorial mutagenesis and selection

27 September 2017

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Directed evolution of an aspartate aminotransferase with new substrate specificities

27 September 2017

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Exploring sequence constraints on an interhelical turn using in vivo selection for catalytic activity

27 September 2017

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Exploring the active site of chorismate mutase by combinatorial mutagenesis and selection: the importance of electrostatic catalysis

27 September 2017

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Linking an easily detectable phenotype to the folding of a common structural motif. Selection of rare turn mutations that prevent the folding of Rop.

27 September 2017

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Periodicity of polar and nonpolar amino acids is the major determinant of secondary structure in self-assembling oligomeric peptides

27 September 2017

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Identification of protein folds: matching hydrophobicity patterns of sequence sets with solvent accessibility patterns of known structures

27 September 2017

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A co-evolution theory of the genetic code

27 September 2017

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A ribozyme that lacks cytidine

27 September 2017

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The aroQ and pheA domains of the bifunctional P-protein from Xanthomonas campestris in a context of genomic comparison

30 May 2018

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A small, thermostable, and monofunctional chorismate mutase from the archaeon Methanococcus jannaschii

30 May 2018

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Protein design by binary patterning of polar and nonpolar amino acids

21 January 2018

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Site-directed mutagenesis of monofunctional chorismate mutase engineered from the E. coli P-protein.

21 January 2018

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21 January 2018

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Cooperative thermal denaturation of proteins designed by binary patterning of polar and nonpolar amino acids

21 January 2018

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Isolation of new ribozymes from a large pool of random sequences [see comment]

21 January 2018

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UGA read-through artifacts--when popular gene expression systems need a pATCH

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/11535813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Error analysis of chemically synthesized polynucleotides

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