PPAR delta: a dagger in the heart of the metabolic syndrome (Q24541527)

6 July 2017

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title

PPAR delta: a dagger in the heart of the metabolic syndrome (English)

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6 July 2017

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Ronald M Evans

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author name string

Grant D Barish

series ordinal

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6 July 2017

Vihang A Narkar

series ordinal

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6 July 2017

language of work or name

English

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publication date

1 March 2006

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Journal of Clinical Investigation

6 July 2017

published in

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6 July 2017

volume

116

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6 July 2017

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6 July 2017

page(s)

590-597

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Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta

6 July 2017

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24 March 2017

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24 March 2017

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24 March 2017

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24 March 2017

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7 April 2017

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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

7 April 2017

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7 April 2017

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7 April 2017

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

7 April 2017

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7 April 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.

27 September 2017

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Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma

27 September 2017

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PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine

27 September 2017

1 reference

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Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle

27 September 2017

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NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching

27 September 2017

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The role of corepressors in transcriptional regulation by nuclear hormone receptors

27 September 2017

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Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes

27 September 2017

1 reference

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PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages

27 September 2017

1 reference

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PPARdelta is a very low-density lipoprotein sensor in macrophages

27 September 2017

1 reference

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The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages

27 September 2017

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The importance of clinical research: the role of thermogenesis in human obesity

27 September 2017

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Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells

27 September 2017

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Corepressors and nuclear hormone receptor function.

27 September 2017

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Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators

27 September 2017

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Peroxisome proliferator-activated receptor delta (PPARdelta )-mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling

27 September 2017

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27 September 2017

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Muscle plasticity and metabolism: effects of exercise and chronic diseases

27 September 2017

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Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

27 September 2017

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The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study

27 September 2017

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Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle

27 September 2017

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Activation of PPARdelta alters lipid metabolism in db/db mice.

30 May 2018

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Activators of the nuclear receptor PPARgamma enhance colon polyp formation

30 May 2018

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Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

30 May 2018

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Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

30 May 2018

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Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

30 May 2018

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The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice

19 June 2018

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Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes

29 November 2018

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Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

29 November 2018

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Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome

29 November 2018

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Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control

29 November 2018

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Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

29 November 2018

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Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response

29 November 2018

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Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability

29 November 2018

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29 November 2018

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Peroxisome proliferator-activated receptor delta is up-regulated during vascular lesion formation and promotes post-confluent cell proliferation in vascular smooth muscle cells

29 November 2018

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29 November 2018

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Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides

29 November 2018

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29 November 2018

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Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models

29 November 2018

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12 December 2020

Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2

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12 December 2020

Alteration of muscle fiber composition linking to insulin resistance and hypertension in fructose-fed rats

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12 December 2020

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12 December 2020

Skeletal muscle fiber composition is related to adiposity and in vitro glucose transport rate in humans

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12 December 2020

Interrelationships between muscle morphology, insulin action, and adiposity

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12 December 2020

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

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12 December 2020

Point: the metabolic syndrome still lives

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12 December 2020

Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans

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12 December 2020

Functional Relationship between MyoD and Peroxisome Proliferator-Activated Receptor-Dependent Regulatory Pathways in the Control of the Human Uncoupling Protein-3 Gene Transcription

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12 December 2020

High density lipoprotein cholesterol and mortality. The Framingham Heart Study

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12 December 2020

Identifiers

DOI

10.1172/JCI27955

1 reference

OpenCitations bibliographic resource ID

6 July 2017

3406943

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

6 July 2017

1 reference