Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. (Q24540063)

6 July 2017

title

Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. (English)

1 reference

ORCID Public Data File 2021

6 July 2017

0 references

1 reference

Yi Qiu

1 reference

author name string

Min Guo

series ordinal

1 reference

6 July 2017

Suming Huang

series ordinal

1 reference

6 July 2017

Roland Stein

series ordinal

1 reference

6 July 2017

language of work or name

English

0 references

publication date

1 January 2002

1 reference

Molecular and Cellular Biology

6 July 2017

published in

1 reference

6 July 2017

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6 July 2017

1 reference

6 July 2017

page(s)

412-420

1 reference

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

6 July 2017

cites work

1 reference

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Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

24 March 2017

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Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

24 March 2017

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Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

24 March 2017

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Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells

24 March 2017

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Human p300 protein is a coactivator for the transcription factor MyoD

24 March 2017

1 reference

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Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins

24 March 2017

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Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator

24 March 2017

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p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein

24 March 2017

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The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells

24 March 2017

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Synergistic role of E1A-Binding proteins and tissue-specific transcription factors in differentiation

24 March 2017

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Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300

24 March 2017

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Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets

24 March 2017

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PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

24 March 2017

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Insulin-promoter-factor 1 is required for pancreas development in mice

7 April 2017

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Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

7 April 2017

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Firefly luciferase gene: structure and expression in mammalian cells

7 April 2017

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The RIPE3b1 activator of the insulin gene is composed of a protein(s) of approximately 43 kDa, whose DNA binding activity is inhibited by protein phosphatase treatment.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter

27 September 2017

1 reference

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The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Pancreatic islet development

27 September 2017

1 reference

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Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

27 September 2017

1 reference

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Functional characterization of the transactivation properties of the PDX-1 homeodomain protein

27 September 2017

1 reference

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Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes

27 September 2017

1 reference

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Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters

27 September 2017

1 reference

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The E2A gene product contains two separable and functionally distinct transcription activation domains

27 September 2017

1 reference

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Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription.

27 September 2017

1 reference

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Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression

27 September 2017

1 reference

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Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

27 September 2017

1 reference

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Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

IPF1, a homeodomain-containing transactivator of the insulin gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Pancreatic expression of human insulin gene in transgenic mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Insulin gene enhancer activity is inhibited by adenovirus 5 E1a gene products

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Retinoblastoma protein family in cell cycle and cancer: a review

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

p300 and CBP as transcriptional regulators and targets of oncogenic events.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

The beta cell transcription factors and development of the pancreas

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice.

30 May 2018

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The insulin gene contains multiple transcriptional elements that respond to glucose

30 May 2018

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The insulin gene promoter. A simplified nomenclature

30 May 2018

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Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

The p300/CBP family: integrating signals with transcription factors and chromatin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139753

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

29 November 2018

1 reference

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A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferase

29 November 2018

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12 December 2020

Structure and evolution of the insulin gene

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12 December 2020

Function of the human insulin promoter in primary cultured islet cells

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12 December 2020

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

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12 December 2020

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

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12 December 2020

XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor

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12 December 2020

Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth

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12 December 2020

Retinoblastoma protein family in cell cycle and cancer: A review

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Crossref

https://api.crossref.org/works/10.1128%2FMCB.22.2.412-420.2002

7 January 2021

inferred from DOI database lookup

Characterization of the functional domains on the C-terminal region of caldesmon using full-length and mutant caldesmon molecules

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FMCB.22.2.412-420.2002

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1128/MCB.22.2.412-420.2002

1 reference

release_abxq5oaxgnapdi2cksgosd2mre

6 July 2017

Fatcat ID

0 references

PMC publication ID

139753

1 reference

6 July 2017

1 reference