Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin (Q24536083)

peptidylprolyl isomerase A

1 reference

Protein phosphatase 3 catalytic subunit alpha

1 reference

cyclosporin A binding

1 reference

1 reference

Stephen C Harrison

Stephen C

Harrison

1 reference

PubMed publication ID

19 October 2023

Lei Jin

Lei

Jin

1 reference

PubMed publication ID

12357034

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

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publication date

15 October 2002

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published in

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volume

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issue

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page(s)

13522-6

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cites work

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

1 reference

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Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

24 March 2017

1 reference

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X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129706

Improved binding affinity for cyclophilin A by a cyclosporin derivative singly modified at its effector domain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129706

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129706

The CCP4 suite: programs for protein crystallography

24 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

24 March 2017

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24 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

22 April 2017

1 reference

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Calcineurin: from structure to function

24 March 2017

1 reference

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Calcineurin mutants render T lymphocytes resistant to cyclosporin A.

27 September 2017

1 reference

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Cyclosporins. Structure-activity relationships

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129706

Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition

27 September 2017

1 reference

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Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B

27 September 2017

1 reference

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Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center.

27 September 2017

1 reference

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X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

30 May 2018

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

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Cyclophilin residues that affect noncompetitive inhibition of the protein serine phosphatase activity of calcineurin by the cyclophilin.cyclosporin A complex

21 January 2018

1 reference

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The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12357034

12 December 2020

inferred from PubMed ID database lookup

Structure-based design of a cyclophilin-calcineurin bridging ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/12357034

12 December 2020

inferred from PubMed ID database lookup

Solution structure of the cyclosporin A/cyclophilin complex by NMR

1 reference

https://pubmed.ncbi.nlm.nih.gov/12357034

12 December 2020

inferred from PubMed ID database lookup

Calcineurin: From structure to function

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.212504399

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1073/PNAS.212504399

1 reference

release_dtpysass3nc6dpaoulg5iyevry

0 references

0 references

2294930

1 reference

1 reference

2294930

PubMed publication ID

12357034

1 reference