The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF (Q24522770)

3 July 2017

title

The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF (English)

1 reference

3 July 2017

0 references

T Inukai

Inukai

1 reference

3 July 2017

T Inaba

series ordinal

author given names

author last names

Inaba

1 reference

3 July 2017

S Ikushima

series ordinal

author given names

author last names

Ikushima

1 reference

3 July 2017

A T Look

series ordinal

author given names

A T

author last names

Look

1 reference

3 July 2017

language of work or name

English

0 references

publication date

1 October 1998

1 reference

Molecular and Cellular Biology

3 July 2017

published in

1 reference

3 July 2017

1 reference

3 July 2017

1 reference

3 July 2017

page(s)

6035-6043

1 reference

Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

3 July 2017

cites work

1 reference

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Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

24 March 2017

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The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties

24 March 2017

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DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein

24 March 2017

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B-cell-specific DNA binding by an E47 homodimer

24 March 2017

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Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

24 March 2017

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A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

24 March 2017

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Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

24 March 2017

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Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: clinical features and molecular pathogenesis

24 March 2017

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Structure and function of helix-loop-helix proteins

24 March 2017

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

24 March 2017

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The helix-loop-helix gene E2A is required for B cell formation

24 March 2017

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Apoptosis in the pathogenesis and treatment of disease

24 March 2017

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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

24 March 2017

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Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis

24 March 2017

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Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

24 March 2017

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

24 March 2017

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The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

24 March 2017

1 reference

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TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins

24 March 2017

1 reference

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Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

24 March 2017

1 reference

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STATs and Gene Regulation

24 March 2017

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Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

7 April 2017

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Induction of apoptosis in fibroblasts by c-myc protein

7 April 2017

1 reference

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Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.

7 April 2017

1 reference

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Cell transformation mediated by homodimeric E2A-HLF transcription factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

27 September 2017

1 reference

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Molecular thanatopsis: a discourse on the BCL2 family and cell death.

27 September 2017

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The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells

27 September 2017

1 reference

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A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells

27 September 2017

1 reference

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ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation

27 September 2017

1 reference

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Positive and negative transcriptional control by the TAL1 helix-loop-helix protein

27 September 2017

1 reference

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Regulation of G1 progression by E2A and Id helix-loop-helix proteins

27 September 2017

1 reference

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E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Bcl-2 initiates a new category of oncogenes: regulators of cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Oncogenic Transcription Factors in the Human Acute Leukemias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Both E12 and E47 allow commitment to the B cell lineage

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Synergistic activation of transcription is mediated by the N-terminal domain of Drosophila fushi tarazu homeoprotein and can occur without DNA binding by the protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining

30 May 2018

1 reference

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Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

30 May 2018

1 reference

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Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain

30 May 2018

1 reference

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Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos

30 May 2018

1 reference

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Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

Chromosomal translocations in human cancer.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109189

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

29 November 2018

2 references

PubMed

https://pubmed.ncbi.nlm.nih.gov/9742120

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crossref

https://api.crossref.org/works/10.1128%2FMCB.18.10.6035

inferred from DOI database lookup

7 January 2021

based on heuristic

Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9742120

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.18.10.6035

1 reference

release_4ojhiva3kveglj3scr3sonpnyu

3 July 2017

Fatcat ID

0 references

PMC publication ID

109189

0 references

1 reference