AMP-activated protein kinase downregulates Kv7.1 cell surface expression (Q24338892)

Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1.

GOA release 2020-03-11

0 references

Thomas Jespersen

0 references

Martin N Andersen

0 references

Hanne B Rasmussen

0 references

Katarzyna Krzystanek

0 references

language of work or name

English

0 references

publication date

January 2012

0 references

0 references

0 references

0 references

143-56

0 references

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Strychnine-blocked glycine receptor is removed from synapses by a shift in insertion/degradation equilibrium

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Ion transport mechanisms responsible for K+ secretion and the transepithelial voltage across marginal cells of stria vascularis in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

LKB1 and AMPK in cell polarity and division

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Diversity of degradation signals in the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The cardiac K+ channel KCNQ1 is essential for gastric acid secretion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

KCNQ1-dependent transport in renal and gastrointestinal epithelia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

AMP-activated protein kinase regulates the assembly of epithelial tight junctions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Regulated assembly of tight junctions by protein kinase C

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Enac degradation in A6 cells by the ubiquitin-proteosome proteolytic pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Insulin and contraction stimulate exocytosis, but increased AMP-activated protein kinase activity resulting from oxidative metabolism stress slows endocytosis of GLUT4 in cardiomyocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Protein kinase Czeta-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Small molecule antagonizes autoinhibition and activates AMP-activated protein kinase in cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Emerging role of AMP-activated protein kinase in coupling membrane transport to cellular metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Correlation between cell-cell contact formation and activation of protein kinase C in a human squamous cell carcinoma cell line

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

AMP-activated protein kinase: a core signalling pathway in the heart.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Kv7.1 surface expression is regulated by epithelial cell polarization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Role of the energy sensor AMP-activated protein kinase in renal physiology and disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The KCNQ1 potassium channel: from gene to physiological function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Ubiquitylation of ion channels

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

The N-terminal juxtamembranous domain of KCNQ1 is critical for channel surface expression: implications in the Romano-Ward LQT1 syndrome.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Glucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021

Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01295.X

7 January 2021