Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradation (Q24336114)

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Monika C Brunner-Weinzierl

21 November 2024

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M. C. Brunner-Weinzierl

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21 November 2024

M. Neumann

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21 November 2024

S. Klar

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A. Wilisch-Neumann

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E. Hollenbach

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S. Kavuri

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M. Leverkus

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R. Kandolf

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K. Klingel

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21 November 2024

language of work or name

English

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publication date

26 May 2011

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10 January 2011

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full work available at URL

21 November 2024

https://www.nature.com/articles/onc2010580.pdf

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Portable Document Format

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https://api.crossref.org/works/10.1038/ONC.2010.580

https://www.nature.com/articles/onc2010580

21 November 2024

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https://api.crossref.org/works/10.1038/ONC.2010.580

21 November 2024

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2485-92

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cites work

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Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

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GSK-3: tricks of the trade for a multi-tasking kinase

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

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Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation.

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The aurora kinase A regulates GSK-3beta in gastric cancer cells

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Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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Signal-specific and phosphorylation-dependent RelB degradation: a potential mechanism of NF-kappaB control

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RelB forms transcriptionally inactive complexes with RelA/p65.

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Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

21 January 2018

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Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

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Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription

21 January 2018

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GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity

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Inhibition of glycogen synthase kinase 3beta suppresses coxsackievirus-induced cytopathic effect and apoptosis via stabilization of beta-catenin

21 January 2018

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IKKbeta phosphorylates p65 at S468 in transactivaton domain 2.

21 January 2018

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The glycogen synthase kinase (GSK) 3beta represses RNA polymerase I transcription

31 March 2020

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Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.580

Dimensions Publication ID

21 November 2024

Identifiers

DOI

10.1038/ONC.2010.580

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1047000020

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Fatcat ID

release_3prgedufmjaangsxluy3avvttq

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