A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression (Q24322269)

10.1016/J.CCR.2011.07.008

DOI

https://api.crossref.org/works/10.1016/J.CCR.2011.07.008

9 December 2024

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Yu-Ru Lee

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9 December 2024

Yeong-Shiau Pu

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9 December 2024

Pei-Wen Hsiao

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9 December 2024

author name string

Wei-Chien Yuan

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Shiu-Feng Huang

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Yu-Min Lin

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Tzu-Yin Chen

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Hsiang-Ching Chung

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Chin-Hsien Tsai

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Hsin-Yi Chen

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Cheng-Ta Chiang

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Chun-Kai Lai

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Li-Ting Lu

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Chun-Hau Chen

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De-Leung Gu

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Yuh-Shan Jou

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Kun Ping Lu

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Hsiu-Ming Shih

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Ruey-Hwa Chen

full work available at URL

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language of work or name

English

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publication date

16 August 2011

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http://www.cell.com/article/S1535610811002637/pdf

file format

Portable Document Format

online access status

open access

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9 December 2024

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10.1016/J.CCR.2011.07.008

DOI

https://api.crossref.org/works/10.1016/J.CCR.2011.07.008

https://api.elsevier.com/content/article/PII:S1535610811002637?httpAccept=text/plain

9 December 2024

1 reference

10.1016/J.CCR.2011.07.008

DOI

https://api.crossref.org/works/10.1016/J.CCR.2011.07.008

9 December 2024

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0 references

214-28

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1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2011.07.008

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Hypoxia, inflammation, and the tumor microenvironment in metastatic disease

1 reference

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

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PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3.

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Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors

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Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

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A human peptidyl-prolyl isomerase essential for regulation of mitosis

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E6AP promotes the degradation of the PML tumor suppressor

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New insights into the role of PML in tumour suppression

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The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses

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Identification of a tumour suppressor network opposing nuclear Akt function

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PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

1 reference

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7 January 2021

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

1 reference

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7 January 2021

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

1 reference

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Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

1 reference

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Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

1 reference

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7 January 2021

Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.

1 reference

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Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α

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7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

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7 January 2021

Promyelocytic leukemia protein controls cell migration in response to hydrogen peroxide and insulin-like growth factor-1

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The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome

1 reference

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7 January 2021

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

1 reference

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7 January 2021

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

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7 January 2021

Loss of the tumor suppressor PML in human cancers of multiple histologic origins

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Role of PML in cell growth and the retinoic acid pathway

1 reference

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Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells

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Characterization of endogenous human promyelocytic leukemia isoforms

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The BTB-Kelch protein KLEIP controls endothelial migration and sprouting angiogenesis.

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Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia

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The number of PML nuclear bodies increases in early S phase by a fission mechanism

1 reference

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