Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation (Q24322026)

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Kwangmin Cho

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Sunglim Cho

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Ilkwon Kim

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Changhoon Oh

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Kwangseog Ahn

EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex

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language of work or name

English

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publication date

20 January 2010

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363-75

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cites work

1 reference

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BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex

19 March 2017

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OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

19 March 2017

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Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing

19 March 2017

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Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

19 March 2017

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

19 March 2017

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A membrane protein required for dislocation of misfolded proteins from the ER

19 March 2017

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The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

19 March 2017

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A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

19 March 2017

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

19 March 2017

1 reference

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Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain

19 March 2017

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Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

19 March 2017

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Roles of protein-disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in endoplasmic reticulum-associated degradation

19 March 2017

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Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

19 March 2017

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

19 March 2017

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

19 March 2017

1 reference

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ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER

19 March 2017

1 reference

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Signal peptide peptidase is required for dislocation from the endoplasmic reticulum

19 March 2017

1 reference

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EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

19 March 2017

1 reference

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Identification of signal peptide peptidase, a presenilin-type aspartic protease

19 March 2017

1 reference

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Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44

19 March 2017

1 reference

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Quality control in the endoplasmic reticulum

19 March 2017

1 reference

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The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

7 April 2017

1 reference

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Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin

7 April 2017

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27 September 2017

ER stress and diseases.

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Signal peptide peptidase (SPP) dimer formation as assessed by fluorescence lifetime imaging microscopy (FLIM) in intact cells

27 September 2017

1 reference

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Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants

27 September 2017

1 reference

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Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.

27 September 2017

1 reference

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Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation

27 September 2017

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The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins.

27 September 2017

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Dynamic retention of Ero1alpha and Ero1beta in the endoplasmic reticulum by interactions with PDI and ERp44.

27 September 2017

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Subtle sequence variation among MHC class I locus products greatly influences sensitivity to HCMV US2- and US11-mediated degradation

27 September 2017

1 reference

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ERp29 triggers a conformational change in polyomavirus to stimulate membrane binding

27 September 2017

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Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation

27 September 2017

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Structure of the human class I histocompatibility antigen, HLA-A2.

27 September 2017

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Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation

27 September 2017

1 reference

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Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).

27 September 2017

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Human cytomegalovirus US3 chimeras containing US2 cytosolic residues acquire major histocompatibility class I and II protein degradation properties

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

The HCMV gene products US11 and US2 differ in their ability to attack allelic forms of murine major histocompatibility complex (MHC) class I heavy chains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

A misassembled transmembrane domain of a polytopic protein associates with signal peptide peptidase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824452

EDEM contributes to maintenance of protein folding efficiency and secretory capacity.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

The MHC class I homolog of human cytomegalovirus is resistant to down-regulation mediated by the unique short region protein (US)2, US3, US6, and US11 gene products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

US2, a Human Cytomegalovirus-encoded Type I Membrane Protein, Contains a Non-cleavable Amino-terminal Signal Peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.359

PURIFICATION AND PROPERTIES OF A MICROSOMAL ENZYME SYSTEM CATALYZING THE REACTIVATION OF REDUCED RIBONUCLEASE AND LYSOZYME

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19942855

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lectins sweet-talk proteins into ERAD

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19942855

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2009.359

1 reference

1 reference

1 reference

PubMed publication ID

19942855

1 reference