Involvement of U1 small nuclear ribonucleoproteins (snRNP) in 5' splice site-U1 snRNP interaction (Q24322003)

single-stranded RNA binding

GOA release 2020-03-11

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ribonucleoprotein complex

GOA release 2020-03-11

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J Tazi

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F Rossi

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T Forné

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E Antoine

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C Brunel

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G Cathala

Journal of Biological Chemistry

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language of work or name

English

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publication date

27 September 1996

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published in

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volume

271

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issue

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page(s)

23985-91

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cites work

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A mechanism for RNA splicing

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Are snRNPs involved in splicing?

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Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast

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Association of U6 snRNA with the 5'-splice site region of pre-mRNA in the spliceosome

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Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes

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U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction with U4/U6

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SR proteins: a conserved family of pre-mRNA splicing factors

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Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

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Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

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Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps

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U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements.

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U1-U2 snRNPs interaction induced by an RNA complementary to the 5' end sequence of U1 snRNA

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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A protein that specifically recognizes the 3' splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein

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Disruption of base pairing between the 5' splice site and the 5' end of U1 snRNA is required for spliceosome assembly

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Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs

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The 5' splice site consensus RNA oligonucleotide induces assembly of U2/U4/U5/U6 small nuclear ribonucleoprotein complexes

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U4/U5/U6 snRNP recognizes the 5' splice site in the absence of U2 snRNP.

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Conserved structures and diversity of functions of RNA-binding proteins

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Homodimerization of the human U1 snRNP-specific protein C

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A compensatory base change in U1 snRNA suppresses a 5' splice site mutation

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Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

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Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

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Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing

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Mutations in yeast U5 snRNA alter the specificity of 5' splice-site cleavage

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U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites

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Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing

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Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

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Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP

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SR proteins can compensate for the loss of U1 snRNP functions in vitro

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U1-specific protein C needed for efficient complex formation of U1 snRNP with a 5' splice site

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Purification of the individual snRNPs U1, U2, U5 and U4/U6 from HeLa cells and characterization of their protein constituents

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inferred from DOI database lookup

7 January 2021

based on heuristic

Mutations in the conserved loop of human U5 snRNA generate use of novel cryptic 5' splice sites in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.39.23985