Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes (Q24321117)

Cholinergic receptor muscarinic 5

GOA release 2020-03-11

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phosphatidylinositol phospholipase C activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

J S Gutkind

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E A Novotny

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M R Brann

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K C Robbins

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

1 June 1991

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published in

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volume

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issue

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page(s)

4703-7

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cites work

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Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors

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Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

19 March 2017

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Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

19 March 2017

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Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes

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Identification of a family of muscarinic acetylcholine receptor genes

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ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

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Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

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Cloned M1 muscarinic receptors mediate both adenylate cyclase inhibition and phosphoinositide turnover

19 March 2017

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Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

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Molecular cloning of integrated Gardner-Rasheed feline sarcoma virus: genetic structure of its cell-derived sequence differs from that of other tyrosine kinase-coding onc genes

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Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

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Opposing effects of a ras oncogene on growth factor-stimulated phosphoinositide hydrolysis: desensitization to platelet-derived growth factor and enhanced sensitivity to bradykinin

27 September 2017

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Stimulation of arachidonic acid release and inhibition of mitogenesis by cloned genes for muscarinic receptor subtypes stably expressed in A9 L cells

27 September 2017

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Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

27 September 2017

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Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets

27 September 2017

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Platelet tyrosine-specific protein phosphorylation is regulated by thrombin

27 September 2017

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Alterations of G-protein coupling function in phosphoinositide signaling pathways of cells transformed by ras and other membrane-associated and cytoplasmic oncogenes

27 September 2017

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Serotonin as a growth factor

27 September 2017

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27 September 2017

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Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

27 September 2017

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Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene

30 May 2018

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Cloned muscarinic receptor subtypes expressed in A9 L cells differ in their coupling to electrical responses.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51734

Serotonin stimulates DNA synthesis in fibroblasts acting through 5-HT1B receptors coupled to a Gi-protein

30 May 2018

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Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production

30 May 2018

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An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover

30 May 2018

1 reference

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Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51734

Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.

30 May 2018

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Selective coupling with K+ currents of muscarinic acetylcholine receptor subtypes in NG108-15 cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51734

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51734

Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet activation and comparisons with the adenylate cyclas

29 November 2018

1 reference

12 December 2020

Evidence that the v-sis gene product transforms by interaction with the receptor for platelet-derived growth factor

1 reference

12 December 2020

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1 reference

12 December 2020

Chemotactic factor induced tyrosine phosphorylation of membrane associated proteins in rabbit peritoneal neutrophils

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.88.11.4703

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ADS bibcode

1991PNAS...88.4703G

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1 reference

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PubMed publication ID

1905013

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