The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene (Q24312426)

Cell division cycle 73

1 reference

peroxisomal biogenesis factor 2

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LEO1 homolog, Paf1/RNA polymerase II complex component

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author name string

Ling Lin

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Jian-Hua Zhang

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Leelamma M Panicker

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William F Simonds

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

11 November 2008

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published in

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volume

105

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issue

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page(s)

17420-5

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cites work

Parafibromin inhibits cancer cell growth and causes G1 phase arrest

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Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II

19 March 2017

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Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo

19 March 2017

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The human PAF complex coordinates transcription with events downstream of RNA synthesis

19 March 2017

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The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II

19 March 2017

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The parafibromin tumor suppressor protein is part of a human Paf1 complex

19 March 2017

1 reference

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Germline and de novo mutations in the HRPT2 tumour suppressor gene in familial isolated hyperparathyroidism (FIHP)

19 March 2017

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HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours

19 March 2017

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Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function

19 March 2017

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Perturbations of the AKT signaling pathway in human cancer

27 September 2017

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p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest

27 September 2017

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Parafibromin, product of the hyperparathyroidism-jaw tumor syndrome gene HRPT2, regulates cyclin D1/PRAD1 expression

27 September 2017

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Familial isolated hyperparathyroidism is rarely caused by germline mutation in HRPT2, the gene for the hyperparathyroidism-jaw tumor syndrome.

27 September 2017

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Somatic and Germ-Line Mutations of theHRPT2Gene in Sporadic Parathyroid Carcinoma

27 September 2017

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Hyperparathyroidism-jaw tumour syndrome

27 September 2017

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HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome

27 September 2017

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Ras enhances Myc protein stability.

27 September 2017

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Intrinsic sites of transcription termination and pausing in the c-myc gene

27 September 2017

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c-myc protein expression in untransformed fibroblasts

27 September 2017

1 reference

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The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region

30 May 2018

1 reference

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Diagnosis of parathyroid tumors in familial isolated hyperparathyroidism with HRPT2 mutation: implications for cancer surveillance.

21 January 2018

1 reference

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Parafibromin mutations in hereditary hyperparathyroidism syndromes and parathyroid tumours.

21 January 2018

1 reference

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Ras mediates cell survival by regulating tuberin

21 January 2018

1 reference

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Accumulation of nonphosphorylated beta-catenin and c-myc in primary and uremic secondary hyperparathyroid tumors

21 January 2018

1 reference

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Hereditary hyperparathyroidism and multiple ossifying jaw fibromas: a clinically and genetically distinct syndrome

21 January 2018

1 reference

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Genetic analyses in patients with familial isolated hyperparathyroidism and hyperparathyroidism-jaw tumour syndrome

29 November 2018

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12 December 2020

Genetic analyses of the HRPT2 gene in primary hyperparathyroidism: germline and somatic mutations in familial and sporadic parathyroid tumors

1 reference

12 December 2020

Surveillance for early detection of aggressive parathyroid disease: carcinoma and atypical adenoma in familial isolated hyperparathyroidism associated with a germline HRPT2 mutation

1 reference

12 December 2020

Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells.

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0710725105

1 reference

release_ktw3yap2ynd67eiuryycbsyaqq

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ktw3yap2ynd67eiuryycbsyaqq

24 November 2022

mapped directly with Wikidata item

3401312

1 reference

1 reference

3401312

PubMed publication ID

18987311

1 reference