The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER (Q24311488)

GOA release 2020-03-11

protein ubiquitination

1 reference

Helen R Stagg

Helen R

Stagg

1 reference

19 October 2023

Emmanuel J H J Wiertz

object named as

Emmanuel J H J Wiertz

Emmanuel J H J

Wiertz

1 reference

19 October 2023

Mair Thomas

Mair

Thomas

1 reference

19 October 2023

Dick van den Boomen

Dick

van den Boomen

1 reference

19 October 2023

Harry A Drabkin

Harry A

Drabkin

1 reference

19 October 2023

Robert M Gemmill

Robert M

Gemmill

1 reference

19 October 2023

Paul J Lehner

Paul J

Lehner

1 reference

describes a project that uses

19 October 2023

language of work or name

English

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publication date

7 September 2009

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published in

Journal of Cell Biology

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volume

186

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issue

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page(s)

685-92

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ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2742190/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

One step at a time: endoplasmic reticulum-associated degradation

1 reference

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Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

19 March 2017

1 reference

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RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene

19 March 2017

1 reference

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Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

19 March 2017

1 reference

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The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

19 March 2017

1 reference

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Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

19 March 2017

1 reference

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Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

19 March 2017

1 reference

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

19 March 2017

1 reference

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A membrane protein required for dislocation of misfolded proteins from the ER

19 March 2017

1 reference

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A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

19 March 2017

1 reference

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Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

19 March 2017

1 reference

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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

19 March 2017

1 reference

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The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway

19 March 2017

1 reference

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The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8

19 March 2017

1 reference

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

19 March 2017

1 reference

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Signal peptide peptidase is required for dislocation from the endoplasmic reticulum

19 March 2017

1 reference

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Selective export of HLA-F by its cytoplasmic tail

19 March 2017

1 reference

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The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

19 March 2017

1 reference

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The ubiquitylation machinery of the endoplasmic reticulum

7 April 2017

1 reference

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SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins

27 September 2017

1 reference

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Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

27 September 2017

1 reference

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A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma

27 September 2017

1 reference

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SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Human cytomegalovirus US3 chimeras containing US2 cytosolic residues acquire major histocompatibility class I and II protein degradation properties

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742190

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200906110

21 January 2018

Identifiers

DOI

10.1083/JCB.200906110

1 reference

release_ol66hq4thjcqpaphovwphfr7yi

Fatcat ID

0 references

1 reference

1 reference

1 reference