CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade (Q24310648)

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Aldons J Lusis

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Omid Kohannim

object named as

Omid Kohannim

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author name string

Imran N Mungrue

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Joanne Pagnon

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Peter S Gargalovic

Variations in DNA elucidate molecular networks that cause disease

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language of work or name

English

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publication date

1 January 2009

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published in

Journal of Immunology

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volume

182

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issue

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page(s)

466-76

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cites work

1 reference

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hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria

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Roles of CHOP/GADD153 in endoplasmic reticulum stress

19 March 2017

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An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

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Human caspase 12 has acquired deleterious mutations

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

19 March 2017

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Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

19 March 2017

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Intracellular signaling by the unfolded protein response

19 March 2017

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7 April 2017

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

19 March 2017

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Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

19 March 2017

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The mammalian unfolded protein response

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Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

27 September 2017

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Cloning and characterization of a putative Ca2+/H+ antiporter gene from Escherichia coli upon functional complementation of Na+/H+ antiporter-deficient strains by the overexpressed gene.

27 September 2017

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GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells

27 September 2017

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The unfolded protein response is an important regulator of inflammatory genes in endothelial cells

30 May 2018

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Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.

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Potassium/proton antiport system of Escherichia coli

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19109178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.182.1.466

1 reference

1 reference

1 reference

PubMed publication ID

19109178

1 reference