Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages (Q24319742)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21179004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages (English)

1 reference

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18 January 2020

1 reference

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18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21179004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Robert Gentleman

1 reference

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18 January 2020

Zizhen Yao

1 reference

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18 January 2020

Carmen G Palii

1 reference

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18 January 2020

Carolina Perez-Iratxeta

1 reference

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18 January 2020

Yi Cao

1 reference

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18 January 2020

Fengtao Dai

1 reference

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18 January 2020

Jerry Davison

1 reference

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18 January 2020

Harold Atkins

1 reference

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18 January 2020

Stephen J Tapscott

1 reference

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18 January 2020

Marjorie Brand

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

21 December 2010

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18 January 2020

1 reference

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18 January 2020

volume

1 reference

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18 January 2020

issue

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18 January 2020

page(s)

494-509

1 reference

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p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis

18 January 2020

cites work

1 reference

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Development of all CD4 T lineages requires nuclear factor TOX

19 March 2017

1 reference

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Beyond the cell cycle: a new role for Cdk6 in differentiation

19 March 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

19 March 2017

1 reference

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Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

19 March 2017

1 reference

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TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3

19 March 2017

1 reference

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The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

19 March 2017

1 reference

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Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

19 March 2017

1 reference

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

19 March 2017

1 reference

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Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy

19 March 2017

1 reference

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Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

19 March 2017

1 reference

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Scl regulates the quiescence and the long-term competence of hematopoietic stem cells

19 March 2017

1 reference

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Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival

19 March 2017

1 reference

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The RUNX genes: gain or loss of function in cancer

19 March 2017

1 reference

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Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells

19 March 2017

1 reference

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The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1

19 March 2017

1 reference

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E protein function in lymphocyte development

19 March 2017

2 references

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19 March 2017

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Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31

19 March 2017

1 reference

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

19 March 2017

1 reference

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Sox-4 facilitates thymocyte differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Characterization of EBV-genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Transcription factor GATA-3 is required for development of the T-cell lineage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming.

27 September 2017

1 reference

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The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

DNA specificity determinants associate with distinct transcription factor functions

27 September 2017

1 reference

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Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells

27 September 2017

1 reference

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High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme

27 September 2017

1 reference

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The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.

27 September 2017

1 reference

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Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis

27 September 2017

1 reference

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Molecular pathogenesis of T-cell leukaemia and lymphoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

A positive role for NLI/Ldb1 in long-range beta-globin locus control region function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Mechanisms of transcription factor deregulation in lymphoid cell transformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

ETS transcription factors and regulation of immunity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

At the crossroads: diverse roles of early thymocyte transcriptional regulators

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

CD69 is an immunoregulatory molecule induced following activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Tal1/SCL binding to pericentromeric DNA represses transcription.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

SCL assembles a multifactorial complex that determines glycophorin A expression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

SCL: from the origin of hematopoiesis to stem cells and leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Identification of a TAL1 Target Gene Reveals a Positive Role for the LIM Domain-Binding Protein Ldb1 in Erythroid Gene Expression and Differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Disruption of differentiation in human cancer: AML shows the way.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

The SCL gene: from case report to critical hematopoietic regulator.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Helix-loop-helix (E2-5, HEB, TAL1 and Id1) protein interaction with the TCRalphadelta enhancers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Activation events during thymic selection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Defective activation and survival of T cells lacking the Ets-1 transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Low SCL/TAL1 expression reveals its major role in adult hematopoietic myeloid progenitors and stem cells

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.342

Expression of CD226 antagonizes apoptotic cell death in murine thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.342

Gene expression profiles during human CD4+ T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.342

How do transcription factors select specific binding sites in the genome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.342

SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.342

Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

Differential expression of cyclin-dependent kinase 6 in cortical thymocytes and T-cell lymphoblastic lymphoma/leukemia

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034015

High expression of ets-1 gene in human thymocytes and immature T leukemic cells

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21179004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21179004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2010.342

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21179004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21179004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21179004

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21179004%20AND%20SRC:MED&resulttype=core&format=json