Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta (Q24317033)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421363%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

title

Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta (English)

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14 December 2019

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GOA release 2020-03-11

Catenin (cadherin associated protein), beta 1

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GOA release 2020-03-11

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1 reference

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14 December 2019

William H Stoothoff

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14 December 2019

Kaihong Mi

series ordinal

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14 December 2019

Sheng-Cai Lin

series ordinal

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14 December 2019

Gail V W Johnson

series ordinal

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14 December 2019

language of work or name

English

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publication date

1 November 2002

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Journal of Neurochemistry

14 December 2019

published in

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14 December 2019

volume

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14 December 2019

issue

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14 December 2019

page(s)

904-913

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Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

14 December 2019

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Recognition of the minimal epitope of monoclonal antibody Tau‐1 depends upon the presence of a phosphate group but not its location

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Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

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Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

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GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity

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Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain

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7 January 2021

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

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7 January 2021

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

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Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

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7 January 2021

Phosphorylation of tau by glycogen synthase kinase 3beta in intact mammalian cells influences the stability of microtubules

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7 January 2021

Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease.

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7 January 2021

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

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7 January 2021

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

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7 January 2021

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

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7 January 2021

Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes

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7 January 2021

A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon

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7 January 2021

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7 January 2021

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7 January 2021

Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction

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7 January 2021

Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.

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7 January 2021

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