Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines (Q24301847)

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English	Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines	scientific article

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31 January 2020

Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines (English)

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31 January 2020

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apoptotic process

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P21 (RAC1) activated kinase 2

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GOA release 2020-03-11

negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

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GOA release 2020-03-11

phosphorylation

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based on heuristic

inferred from title

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Zigang Dong

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Weihong Wen

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Margarita L Malakhova

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Margarita Malakhova

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Hong-Gyum Kim

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Ziming Dong

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31 January 2020

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Xiang Li

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31 January 2020

Kangdong Liu

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31 January 2020

Cong Peng

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Tingting Li

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Weiya Ma

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9 May 2011

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31 January 2020

Journal of Biological Chemistry

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22291-22299

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31 January 2020

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Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8

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P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation

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p21-activated kinases in cancer

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p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

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p21-activated protein kinase gamma-PAK is activated by ionizing radiation and other DNA-damaging agents. Similarities and differences to alpha-PAK

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p21-activated protein kinase gamma-PAK in pituitary secretory granules phosphorylates prolactin

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Caspase-7: a protease involved in apoptosis and inflammation

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PAK signaling in oncogenesis.

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Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death

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Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival.

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Inhibition of the intrinsic apoptosis pathway downstream of caspase-9 activation causes chemotherapy resistance in diffuse large B-cell lymphoma.

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P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation

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Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2

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31 January 2020

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