Cdc2: a monopotent or pluripotent CDK? (Q24300976)

cyclin dependent kinase 1

title

Cdc2: a monopotent or pluripotent CDK? (English)

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main subject

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regulation of embryonic development

GOA release 2020-03-11

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GOA release 2020-03-11

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X Hu

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

L C Moscinski

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

language of work or name

English

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publication date

June 2011

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published in

Cell Proliferation

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

page(s)

205-211

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

Cdk1 is sufficient to drive the mammalian cell cycle

14 May 2020

cites work

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Cdc2-cyclin E complexes regulate the G1/S phase transition

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The E2F1-3 transcription factors are essential for cellular proliferation.

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E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

21 January 2018

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Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

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Preliminary Characterization of the Transcriptional and Translational Products of the Saccharomyces cerevisiae Cell Division Cycle Gene CDC28

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Purification of maturation-promoting factor, an intracellular regulator of early mitotic events

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The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

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G1 phase progression: cycling on cue

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Mammalian cyclin-dependent kinases

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Checking out the G(2)/M transition.

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Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C

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Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

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Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase

21 January 2018

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Regulating mammalian checkpoints through Cdc25 inactivation

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Cell cycle regulation by the Cdc25 phosphatase family

21 January 2018

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Cdc25 phosphatases are required for timely assembly of CDK1-cyclin B at the G2/M transition

21 January 2018

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Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

21 January 2018

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Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25.

21 January 2018

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Positive regulation of Wee1 by Chk1 and 14-3-3 proteins

21 January 2018

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Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation

21 January 2018

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

21 January 2018

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Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

21 January 2018

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Mouse development and cell proliferation in the absence of D-cyclins.

21 January 2018

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Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

21 January 2018

1 reference

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Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

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Cdk2 knockout mice are viable

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

21 January 2018

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Cyclin E ablation in the mouse

21 January 2018

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Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

21 January 2018

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p21 Inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint.

21 January 2018

1 reference

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

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Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1)

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

TGFbeta regulates the expression and activities of G2 checkpoint kinases in human myeloid leukemia cells

21 January 2018

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Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells

21 January 2018

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Cyclin B-cdk1 controls pronuclear union in interphase.

21 January 2018

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The regulation of E2F by pRB-family proteins

21 January 2018

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The Rb/E2F pathway and cancer

21 January 2018

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Human retinoblastoma protein (Rb) is phosphorylated by cdc2 kinase and MAP kinase in Xenopus maturing oocytes.

21 January 2018

1 reference

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Cdc2 and Cdk2 kinase activated by transforming growth factor-beta1 trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

21 January 2018

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Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition.

21 January 2018

1 reference

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p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

E2Fs link the control of G1/S and G2/M transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

SnapShot: forkhead transcription factors I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Forkhead transcription factors II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Overexpression of FoxO1 causes proliferation of cultured pancreatic beta cells exposed to low nutrition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

CDK1 promotes cell proliferation and survival via phosphorylation and inhibition of FOXO1 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Regulation of TGFbeta1-mediated growth inhibition and apoptosis by RUNX2 isoforms in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

21 January 2018

1 reference

12 December 2020

Toward an understanding of the functional complexity of the E2F and retinoblastoma families

1 reference

12 December 2020

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

1 reference

12 December 2020

Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe

1 reference

12 December 2020

Activity of the maturation-promoting factor and the extent of protein phosphorylation oscillate simultaneously during meiotic maturation of starfish oocytes

1 reference

12 December 2020

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

12 December 2020

Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00753.X

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1111/J.1365-2184.2011.00753.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json

14 May 2020

PubMed publication ID

21535261

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496858&resulttype=core&format=json