Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress (Q24300945)

cellular response to DNA damage stimulus

GOA release 2020-03-11

1 reference

Cell cycle checkpoint signaling through the ATM and ATR kinases

GOA release 2020-03-11

1 reference

1 reference

Tony T Huang

0 references

Shelly M Wuerzberger-Davis

series ordinal

0 references

Zhao-Hui Wu

series ordinal

0 references

Shigeki Miyamoto

series ordinal

0 references

language of work or name

English

0 references

publication date

26 November 2003

0 references

published in

Cell

0 references

volume

115

0 references

issue

0 references

page(s)

565-76

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Missing pieces in the NF-kappaB puzzle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Signaling--2000 and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The many substrates and functions of ATM

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

NF-kappaB regulation in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO, ubiquitin's mysterious cousin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO-1 modification activates the transcriptional response of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Regulation of transcriptional activation domain function by ubiquitin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Nuclear and unclear functions of SUMO

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

IkappaB family members function by different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900895-X

7 January 2021

10.1016/S0092-8674(03)00895-X

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

14651848

1 reference

Consolidated OpenCitations Corpus – April 2017