CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability (Q24300796)

URI1 prefoldin like chaperone

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PIH1 domain containing 1

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Telomere maintenance 2

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Hsp90 protein binding

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Telomere maintenance 2

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PIH1 domain containing 1

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RuvB-like protein 2

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Zuzana Horejsí

Zuzana

Horejsí

1 reference

26 November 2023

Helen Flynn

Helen

Flynn

1 reference

26 November 2023

Spencer J Collis

Spencer J

Collis

1 reference

26 November 2023

Titia de Lange

Titia

de Lange

1 reference

26 November 2023

Hiroyuki Takai

Hiroyuki

Takai

1 reference

26 November 2023

Carrie A Adelman

Carrie A

Adelman

1 reference

26 November 2023

Sarah Maslen

Sarah

Maslen

1 reference

26 November 2023

J Mark Skehel

J Mark

Skehel

1 reference

26 November 2023

Simon J Boulton

Simon J

Boulton

1 reference

Molecular interaction network of the Hsp90 chaperone system

26 November 2023

language of work or name

English

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publication date

24 September 2010

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839-50

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cites work

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Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro

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The role of SMG-1 in nonsense-mediated mRNA decay.

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TOR signaling in growth and metabolism

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Tel2 regulates the stability of PI3K-related protein kinases

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Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

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The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4

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FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex

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RVB1/RVB2: running rings around molecular biology

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High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes

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The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks

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C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

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Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

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HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability

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GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

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Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

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Tel2 is required for activation of the Mrc1-mediated replication checkpoint

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HCLK2 is required for activity of the DNA damage response kinase ATR.

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The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

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Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

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Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

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Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.

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Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

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Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits

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Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI

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AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay

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The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

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URI-1 is required for DNA stability in C. elegans

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7 January 2021