Y14 and hUpf3b form an NMD-activating complex (Q24300691)

Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis

GOA release 2020-03-11

Matthias W Hentze

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Niels H Gehring

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Andreas E Kulozik

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object named as

Andreas E Kulozik

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author name string

Gabriele Neu-Yilik

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Thomas Schell

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language of work or name

English

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publication date

April 2003

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939-49

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

The human intronless melanocortin 4-receptor gene is NMD insensitive

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Translation driven by an eIF4G core domain in vivo

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Tethered-function analysis reveals that elF4E can recruit ribosomes independent of its binding to the cap structure.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Translation is required to remove Y14 from mRNAs in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Nonsense-mediated mRNA decay in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Increased efficiency of mRNA 3′ end formation: a new genetic mechanism contributing to hereditary thrombophilia

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

A perfect message: RNA surveillance and nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization?

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

The Y14 protein communicates to the cytoplasm the position of exon-exon junctions

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia?

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

The protein Mago provides a link between splicing and mRNA localization.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

NMR structure of the bacteriophage lambda N peptide/boxB RNA complex: recognition of a GNRA fold by an arginine-rich motif

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Nonsense surveillance in lymphocytes?

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Quality control of mRNA function

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

A protein-RNA interaction network facilitates the template-independent cooperative assembly on RNA polymerase of a stable antitermination complex containing the lambda N protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

RNA events. No end to nonsense

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Splicing and 3' end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Mammalian orthologues of a yeast regulator of nonsense transcript stability

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Cytoplasmic mRNA for human triosephosphate isomerase is immune to nonsense-mediated decay despite forming polysomes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Binary specification of nonsense codons by splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900142-4

7 January 2021

10.1016/S1097-2765(03)00142-4

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12718880

1 reference

Consolidated OpenCitations Corpus – April 2017