Relevance of CD6-mediated interactions in T cell activation and proliferation (Q24300571)

GOA release 2020-03-11

CD6 molecule

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GOA release 2020-03-11

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María Mittelbrunn

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Carlos Enrich

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Francisco Lozano

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Francisco Sánchez-Madrid

object named as

Francisco Sánchez-Madrid

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author name string

Idoia Gimferrer

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Maria Calvo

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Montse Farnós

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Maria Rosa Sarrias

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Jordi Vives

Physical association of CD5 and the T cell receptor/CD3 antigen complex on the surface of human T lymphocytes

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language of work or name

English

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publication date

15 August 2004

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published in

Journal of Immunology

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volume

173

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issue

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page(s)

2262-70

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cites work

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Human CD6 possesses a large, alternatively spliced cytoplasmic domain

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Noncovalent associations of T lymphocyte surface proteins

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Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains.

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Frontline: Optimal T cell activation requires the engagement of CD6 and CD166.

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Conjugation of antibodies with fluorochromes: modifications to the standard methods

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Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy

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Properties of the extracellular calcium binding module of the proteoglycan testican

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A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

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CD6-ligand interactions: a paradigm for SRCR domain function?

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Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy

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Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism

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7 January 2021

The duration of antigenic stimulation determines the fate of naive and effector T cells

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7 January 2021

Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59

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7 January 2021

Mutational analysis of the CD6 binding site in activated leukocyte cell adhesion molecule

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Identification of a natural soluble form of human CD5

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Three-dimensional segregation of supramolecular activation clusters in T cells

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The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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Role of ICAM-3 in the initial interaction of T lymphocytes and APCs

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Simultaneous cross-linking of CD6 and CD28 induces cell proliferation in resting T cells

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Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5

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The membrane-proximal scavenger receptor cysteine-rich domain of CD6 contains the activated leukocyte cell adhesion molecule binding site

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7 January 2021

The amino-terminal immunoglobulin-like domain of activated leukocyte cell adhesion molecule binds specifically to the membrane-proximal scavenger receptor cysteine-rich domain of CD6 with a 1:1 stoichiometry

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Molecular basis for the homophilic activated leukocyte cell adhesion molecule (ALCAM)-ALCAM interaction

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7 January 2021

The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells

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Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins

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7 January 2021

Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors

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7 January 2021

Proliferating dendritic cell progenitors in human blood

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Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells

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Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand

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7 January 2021

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

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7 January 2021

CD6: expression during development, apoptosis and selection of human and mouse thymocytes.

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7 January 2021

Mutational analysis of the CD6 ligand binding domain

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7 January 2021

High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome

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Biochemical characterization of recombinant and circulating human Spalpha.

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Recombinant expression and properties of the human calcium-binding extracellular matrix protein BM-40

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7 January 2021

The immunological synapse.

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7 January 2021

ALCAM (CD166): its role in hematopoietic and endothelial development.

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7 January 2021

OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation

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7 January 2021

The Scavenger Receptor Cysteine-Rich (SRCR) domain: an ancient and highly conserved protein module of the innate immune system

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7 January 2021

CD5 Inhibits Signaling at the Immunological Synapse Without Impairing Its Formation

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7 January 2021