HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A (Q24292517)

Granzyme B

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High mobility group box 2

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SET nuclear proto-oncogene

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author name string

Zusen Fan

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Paul J Beresford

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Dong Zhang

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Judy Lieberman

Molecular and Cellular Biology

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language of work or name

English

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publication date

April 2002

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published in

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volume

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issue

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page(s)

2810-20

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cites work

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Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

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Protein ligands to HuR modulate its interaction with target mRNAs in vivo

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Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

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Novel autoantigens of perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) in ulcerative colitis: non-histone chromosomal proteins, HMG1 and HMG2

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ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

19 March 2017

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The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures

19 March 2017

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Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII

19 March 2017

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Activation of the TFIID-TFIIA complex with HMG-2

19 March 2017

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Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis

19 March 2017

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Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

19 March 2017

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Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

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Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

19 March 2017

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The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Tumor suppression and potentiation by manipulation of pp32 expression

27 September 2017

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DNA damage in the nucleosome core is refractory to repair by human excision nuclease

27 September 2017

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Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.

27 September 2017

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27 September 2017

Going APE over ref-1.

1 reference

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DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

27 September 2017

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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

27 September 2017

1 reference

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27 September 2017

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27 September 2017

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High-mobility group 1/2 proteins are essential for initiating rolling-circle-type DNA replication at a parvovirus hairpin origin.

27 September 2017

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Nuclear targeting of the serine protease granzyme A (fragmentin-1).

27 September 2017

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Granule-mediated killing: pathways for granzyme B-initiated apoptosis.

27 September 2017

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The acidic tail of the high mobility group protein HMG-D modulates the structural selectivity of DNA binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Differential binding of HMG1, HMG2, and a single HMG box to cisplatin-damaged DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

DNA looping by the HMG-box domains of HMG1 and modulation of DNA binding by the acidic C-terminal domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Granzyme A is an interleukin 1 beta-converting enzyme

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Participation of core histone "tails" in the stabilization of the chromatin solenoid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Dissection of Chromosome Structure with Trypsin and Nucleases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Antibodies against chromosomal HMG proteins stain the cytoplasm of mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Cellular localization and expression of template-activating factor I in different cell types.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

A novel M(r) 32,000 nuclear phosphoprotein is selectively expressed in cells competent for self-renewal

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

The high mobility group protein HMG I(Y) is an essential structural component of a virus-inducible enhancer complex

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133744

Identification of the nuclear factor HMG2 as an activator for DFF nuclease activity

29 November 2018

1 reference

12 December 2020

Histone- and chromatin-binding activity of template activating factor-I

1 reference

12 December 2020

HMG box A in HMG2 protein functions as a mediator of DNA structural alteration together with box B

1 reference

12 December 2020

Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

1 reference

12 December 2020

The binding sites for large and small high-mobility-group (HMG) proteins. Studies on HMG-nucleosome interactions in vitro

1 reference

12 December 2020

Antigenic determinants of high mobility group chromosomal proteins 1 and 2

1 reference

12 December 2020

Autoantibodies to nonhistone chromosomal proteins HMG-1 and HMG-2 in sera of patients with juvenile rheumatoid arthritis

1 reference

12 December 2020

The specific interactions of HMG 1 and 2 with negatively supercoiled DNA are modulated by their acidic C-terminal domains and involve cysteine residues in their HMG 1/2 boxes

1 reference

12 December 2020

Stimulation of DNA transcription by the replication factor from the adenovirus genome in a chromatin-like structure

1 reference

12 December 2020

10.1128/MCB.22.8.2810-2820.2002

Identifiers

DOI

1 reference

1 reference

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PubMed publication ID

11909973

1 reference